Acoustic radiation force impulse (ARFI) in the evaluation of liver fibrosis in chronic liver disease: Where do we stand today?

Chronic liver disease (CLD) is common in clinical practice, and the estimation of liver fibrosis (FIB) is crucial for the treatment of these patients. Liver elastography is more widely used in the evaluation of hepatic steatosis and FIB. Acoustic radiation force impulse (ARFIs) are an imaging techni...

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Main Authors: Pradipta C Hande, Vivek Hande
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Marine Medical Society
Subjects:
Online Access:http://www.marinemedicalsociety.in/article.asp?issn=0975-3605;year=2021;volume=23;issue=2;spage=117;epage=123;aulast=Hande
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author Pradipta C Hande
Vivek Hande
author_facet Pradipta C Hande
Vivek Hande
author_sort Pradipta C Hande
collection DOAJ
description Chronic liver disease (CLD) is common in clinical practice, and the estimation of liver fibrosis (FIB) is crucial for the treatment of these patients. Liver elastography is more widely used in the evaluation of hepatic steatosis and FIB. Acoustic radiation force impulse (ARFIs) are an imaging technique which is available on ultrasonography machines to indicate tissue stiffness of various organs as it correlates with tissue elasticity. Various etiologies can cause moderate-to-severe hepatic FIB which can lead to altered liver function with structural and biochemical abnormalities which eventually result in liver failure. Commercially available ultrasound machines with incorporated ability for shear-wave (SW) technology and available software systems can perform ARFI. Usually, curved array 3.5–4 MHz transducers are used for obtaining SW velocities. We aim to review the clinical applications of ARFI as a noninvasive method using SW velocity measurements to assess the severity of liver FIB in liver parenchymal diseases. In this article, we have discussed the efficacy of quantitative assessment to evaluate the severity of liver disease which has a direct impact on the management and outcome of CLD.
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spelling doaj.art-96c1f005a3254da7b694da102118ba502022-12-21T21:32:10ZengWolters Kluwer Medknow PublicationsJournal of Marine Medical Society0975-36052021-01-0123211712310.4103/jmms.jmms_2_21Acoustic radiation force impulse (ARFI) in the evaluation of liver fibrosis in chronic liver disease: Where do we stand today?Pradipta C HandeVivek HandeChronic liver disease (CLD) is common in clinical practice, and the estimation of liver fibrosis (FIB) is crucial for the treatment of these patients. Liver elastography is more widely used in the evaluation of hepatic steatosis and FIB. Acoustic radiation force impulse (ARFIs) are an imaging technique which is available on ultrasonography machines to indicate tissue stiffness of various organs as it correlates with tissue elasticity. Various etiologies can cause moderate-to-severe hepatic FIB which can lead to altered liver function with structural and biochemical abnormalities which eventually result in liver failure. Commercially available ultrasound machines with incorporated ability for shear-wave (SW) technology and available software systems can perform ARFI. Usually, curved array 3.5–4 MHz transducers are used for obtaining SW velocities. We aim to review the clinical applications of ARFI as a noninvasive method using SW velocity measurements to assess the severity of liver FIB in liver parenchymal diseases. In this article, we have discussed the efficacy of quantitative assessment to evaluate the severity of liver disease which has a direct impact on the management and outcome of CLD.http://www.marinemedicalsociety.in/article.asp?issn=0975-3605;year=2021;volume=23;issue=2;spage=117;epage=123;aulast=Handeacoustic radiation force impulsesliver elastographyliver stiffnessshear wave
spellingShingle Pradipta C Hande
Vivek Hande
Acoustic radiation force impulse (ARFI) in the evaluation of liver fibrosis in chronic liver disease: Where do we stand today?
Journal of Marine Medical Society
acoustic radiation force impulses
liver elastography
liver stiffness
shear wave
title Acoustic radiation force impulse (ARFI) in the evaluation of liver fibrosis in chronic liver disease: Where do we stand today?
title_full Acoustic radiation force impulse (ARFI) in the evaluation of liver fibrosis in chronic liver disease: Where do we stand today?
title_fullStr Acoustic radiation force impulse (ARFI) in the evaluation of liver fibrosis in chronic liver disease: Where do we stand today?
title_full_unstemmed Acoustic radiation force impulse (ARFI) in the evaluation of liver fibrosis in chronic liver disease: Where do we stand today?
title_short Acoustic radiation force impulse (ARFI) in the evaluation of liver fibrosis in chronic liver disease: Where do we stand today?
title_sort acoustic radiation force impulse arfi in the evaluation of liver fibrosis in chronic liver disease where do we stand today
topic acoustic radiation force impulses
liver elastography
liver stiffness
shear wave
url http://www.marinemedicalsociety.in/article.asp?issn=0975-3605;year=2021;volume=23;issue=2;spage=117;epage=123;aulast=Hande
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AT vivekhande acousticradiationforceimpulsearfiintheevaluationofliverfibrosisinchronicliverdiseasewheredowestandtoday