The Role of CCL2/CCR2 Axis in Cerebral Ischemia-Reperfusion Injury and Treatment: From Animal Experiments to Clinical Trials

The Role of CCL2/CCR2 Axis in Cerebral Ischemia-Reperfusion Injury and Treatment: From Animal Experiments to Clinical Trials

C-C motif chemokine ligand 2 (CCL2) is a member of the monocyte chemokine protein family, which binds to its receptor CCR2 to induce monocyte infiltration and mediate inflammation. The CCL2/CCR2 signaling pathway participates in the transduction of neuroinflammatory information between all types of...

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Bibliographic Details
Main Authors: Huixia Geng, Luna Chen, Jing Tang, Yi’ang Chen, Lai Wang
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
CCL2
CCR2
cerebral ischemia-reperfusion
neuroinflammation
brain injury
Online Access:https://www.mdpi.com/1422-0067/23/7/3485

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