Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report

The treatment of hemangiomas in infancy may be associated with significant morbidity. In addition to morbidity, an objective response cannot be obtained because of the absence of targeted therapeutic options. Herein, we present an infant with a segmental hemangioma and marked glucocorticoid toxicity...

Full description

Bibliographic Details
Main Authors: Serhan Küpeli, Derya Çimen, Begül Yağcı Küpeli
Format: Article
Language:English
Published: Galenos Publishing House 2012-05-01
Series:Turkish Journal of Hematology
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-37233
_version_ 1828021635273195520
author Serhan Küpeli
Derya Çimen
Begül Yağcı Küpeli
author_facet Serhan Küpeli
Derya Çimen
Begül Yağcı Küpeli
author_sort Serhan Küpeli
collection DOAJ
description The treatment of hemangiomas in infancy may be associated with significant morbidity. In addition to morbidity, an objective response cannot be obtained because of the absence of targeted therapeutic options. Herein, we present an infant with a segmental hemangioma and marked glucocorticoid toxicity due to prior steroid therapy that was successfully treated with propranolol. Propranolol was tolerated well and no side effects were observed during the treatment. The only problem to occur was disease recurrence following the withdrawal of propranolol at age 13 months, which was not within the age of spontaneous regression (generally considered as >18 months).
first_indexed 2024-04-10T11:57:12Z
format Article
id doaj.art-96c832712b5144ad9213026d9b99b73d
institution Directory Open Access Journal
issn 1308-5263
language English
last_indexed 2024-04-10T11:57:12Z
publishDate 2012-05-01
publisher Galenos Publishing House
record_format Article
series Turkish Journal of Hematology
spelling doaj.art-96c832712b5144ad9213026d9b99b73d2023-02-15T16:16:47ZengGalenos Publishing HouseTurkish Journal of Hematology1308-52632012-05-0129217017310.5505/tjh.2012.37233TJH-37233Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case ReportSerhan Küpeli0Derya Çimen1Begül Yağcı Küpeli2Diyarbakır Children's Diseases Hospital, Department Of Pediatric Oncology, Diyarbakır, TurkeyDiyarbakır Children's Diseases Hospital, Department Of Pediatric Cardiology, Diyarbakır, TurkeyDicle University, School Of Medicine, Department Of Pediatric Oncology, Diyarbakır, TurkeyThe treatment of hemangiomas in infancy may be associated with significant morbidity. In addition to morbidity, an objective response cannot be obtained because of the absence of targeted therapeutic options. Herein, we present an infant with a segmental hemangioma and marked glucocorticoid toxicity due to prior steroid therapy that was successfully treated with propranolol. Propranolol was tolerated well and no side effects were observed during the treatment. The only problem to occur was disease recurrence following the withdrawal of propranolol at age 13 months, which was not within the age of spontaneous regression (generally considered as >18 months).https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-37233hemangiomasegmental hemangiomasubglottic hemangiomapropranolol
spellingShingle Serhan Küpeli
Derya Çimen
Begül Yağcı Küpeli
Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
Turkish Journal of Hematology
hemangioma
segmental hemangioma
subglottic hemangioma
propranolol
title Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_full Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_fullStr Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_full_unstemmed Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_short Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_sort successful treatment with propranolol in a patient with a segmental hemangioma a case report
topic hemangioma
segmental hemangioma
subglottic hemangioma
propranolol
url https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-37233
work_keys_str_mv AT serhankupeli successfultreatmentwithpropranololinapatientwithasegmentalhemangiomaacasereport
AT deryacimen successfultreatmentwithpropranololinapatientwithasegmentalhemangiomaacasereport
AT begulyagcıkupeli successfultreatmentwithpropranololinapatientwithasegmentalhemangiomaacasereport