ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION

Aim. The assessment of cardiac hemodynamics in the test with reactive hyperemia in young females with idiopathic arterial hypotension.Material and methods. The comparative analysis was done, of echocardiography in the standard test with reactive hyperemia within brachial area among 72 women with idi...

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Main Authors: V. M. Baev, T. Yu. Agafonova, O. A. Samsonova, R. Sh. Dusakova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2017-10-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/555
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author V. M. Baev
T. Yu. Agafonova
O. A. Samsonova
R. Sh. Dusakova
author_facet V. M. Baev
T. Yu. Agafonova
O. A. Samsonova
R. Sh. Dusakova
author_sort V. M. Baev
collection DOAJ
description Aim. The assessment of cardiac hemodynamics in the test with reactive hyperemia in young females with idiopathic arterial hypotension.Material and methods. The comparative analysis was done, of echocardiography in the standard test with reactive hyperemia within brachial area among 72 women with idiopathic arterial hypotension — systolic blood pressure 94-98 mmHg, and in 37 females normotensive — systolic BP 120-123 mmHg. In both groups the age was 19 (18-22) y.o.Results. Reactive hyperemia in hypotension is followed by a significant increase of maximum velocities relation of the early (peak E) and delayed (peak A) diastolic filling of the left ventricle by 18%. In normotensive women there was no such change of the relation.Conclusion. In young females with idiopathic arterial hypotension the test with reactive hyperemia, as a model of acute hypoxia, is followed by isolated diastolic dysfunction of myocardium. Probably, it is related to the increase of the rate of already existing hypernitricoxidemia, which is a key factors for arterial hypotension pathogenesis.
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spelling doaj.art-96c8cffcb9304ed784a998baa9ab3c7e2023-03-13T07:23:26Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252017-10-01165161910.15829/1728-8800-2017-5-16-19480ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSIONV. M. Baev0T. Yu. Agafonova1O. A. Samsonova2R. Sh. Dusakova3Пермский государственный медицинский университет им. академика Е.А. Вагнера Минздрава РоссииПермский государственный медицинский университет им. академика Е.А. Вагнера Минздрава РоссииПермский государственный медицинский университет им. академика Е.А. Вагнера Минздрава РоссииПермский государственный медицинский университет им. академика Е.А. Вагнера Минздрава РоссииAim. The assessment of cardiac hemodynamics in the test with reactive hyperemia in young females with idiopathic arterial hypotension.Material and methods. The comparative analysis was done, of echocardiography in the standard test with reactive hyperemia within brachial area among 72 women with idiopathic arterial hypotension — systolic blood pressure 94-98 mmHg, and in 37 females normotensive — systolic BP 120-123 mmHg. In both groups the age was 19 (18-22) y.o.Results. Reactive hyperemia in hypotension is followed by a significant increase of maximum velocities relation of the early (peak E) and delayed (peak A) diastolic filling of the left ventricle by 18%. In normotensive women there was no such change of the relation.Conclusion. In young females with idiopathic arterial hypotension the test with reactive hyperemia, as a model of acute hypoxia, is followed by isolated diastolic dysfunction of myocardium. Probably, it is related to the increase of the rate of already existing hypernitricoxidemia, which is a key factors for arterial hypotension pathogenesis.https://cardiovascular.elpub.ru/jour/article/view/555артериальная гипотензиягипероксидазотемияизолированная диастолическая дисфункция
spellingShingle V. M. Baev
T. Yu. Agafonova
O. A. Samsonova
R. Sh. Dusakova
ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
Кардиоваскулярная терапия и профилактика
артериальная гипотензия
гипероксидазотемия
изолированная диастолическая дисфункция
title ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_full ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_fullStr ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_full_unstemmed ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_short ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_sort isolated diastolic dysfunction as a result of hypernitricoxidemia in arterial hypotension
topic артериальная гипотензия
гипероксидазотемия
изолированная диастолическая дисфункция
url https://cardiovascular.elpub.ru/jour/article/view/555
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AT rshdusakova isolateddiastolicdysfunctionasaresultofhypernitricoxidemiainarterialhypotension