Development and Validation of Valganciclovir and its Active Metabolite Ganciclovir Determination in Human Plasma by HPLC-MS/MS Method

Development and Validation of Valganciclovir and its Active Metabolite Ganciclovir Determination in Human Plasma by HPLC-MS/MS Method

Introduction. Currently, physicochemical methods of quantification are actively used to determine the content of drugs in biological fluids. High-performance liquid chromatography with various detection methods is particularly widespread. One of the most difficult practical tasks is the chromatograp...

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Bibliographic Details
Main Authors: T. N. Komarov, I. E. Shohin, M. A. Tokareva, O. A. Archakova, D. S. Bogdanova, A. V. Aleshina, N. S. Bagaeva, V. V. Davydanova
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2021-02-01
Series:Разработка и регистрация лекарственных средств
Subjects:
valganciclovir
ganciclovir
plasma
hplc-ms/ms
validation
bioequivalence
Online Access:https://www.pharmjournal.ru/jour/article/view/898

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