Wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole.
PURPOSE:To determine whether the width of the retinal artery (RA) trajectory was associated with the presence of a macular hole (MH). METHODS:A retrospective cross sectional case-control study was performed. The fundus photographs were rotated 90 degrees, and the coordinates of the best fit curve of...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4395100?pdf=render |
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| author | Naoya Yoshihara Taiji Sakamoto Takehiro Yamashita Toshifumi Yamashita Keita Yamakiri Shozo Sonoda Tatsuro Ishibashi |
| author_facet | Naoya Yoshihara Taiji Sakamoto Takehiro Yamashita Toshifumi Yamashita Keita Yamakiri Shozo Sonoda Tatsuro Ishibashi |
| author_sort | Naoya Yoshihara |
| collection | DOAJ |
| description | PURPOSE:To determine whether the width of the retinal artery (RA) trajectory was associated with the presence of a macular hole (MH). METHODS:A retrospective cross sectional case-control study was performed. The fundus photographs were rotated 90 degrees, and the coordinates of the best fit curve of the RA trajectory were determined automatically based on these plots using the ImageJ program. The converted coordinates were fit to a second degree polynomial (ax2/100 + bx + c) equation. The width and steepness of the RA trajectory, "a", of the eyes with a MH eye were compared to that of the fellow eyes. RESULTS:One hundred and ten eyes of 55 consecutive patients (30 women) with a unilateral MH and healthy fellow eyes were analyzed. The mean age was 64.9 years (range 47-81 years). The constant 'a' was significantly smaller in eyes with a MH than that of the fellow eyes (0.379 ± 0.094 vs 0.416 ± 0.121, P = 0.001, paired t test), indicating that the RA trajectory was wider in the MH eyes than in the fellow eyes. There was a significant correlation between the axial length and 'a' of the RA trajectory in the MH eyes (R = 0.273, P = 0.044) and in the fellow eyes (R = 0.356, P = 0.008; Spearman's rank correlation coefficient). CONCLUSIONS:Because eyes with a MH have a significantly wider and flatter RA trajectory, there may be greater traction on the fovea which is located between the RA arches. The causative role of this finding is still unclear. |
| first_indexed | 2024-04-12T11:53:55Z |
| format | Article |
| id | doaj.art-96ca510f2e704fef967d37095fb93777 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T11:53:55Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-96ca510f2e704fef967d37095fb937772022-12-22T03:34:05ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01104e012287610.1371/journal.pone.0122876Wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole.Naoya YoshiharaTaiji SakamotoTakehiro YamashitaToshifumi YamashitaKeita YamakiriShozo SonodaTatsuro IshibashiPURPOSE:To determine whether the width of the retinal artery (RA) trajectory was associated with the presence of a macular hole (MH). METHODS:A retrospective cross sectional case-control study was performed. The fundus photographs were rotated 90 degrees, and the coordinates of the best fit curve of the RA trajectory were determined automatically based on these plots using the ImageJ program. The converted coordinates were fit to a second degree polynomial (ax2/100 + bx + c) equation. The width and steepness of the RA trajectory, "a", of the eyes with a MH eye were compared to that of the fellow eyes. RESULTS:One hundred and ten eyes of 55 consecutive patients (30 women) with a unilateral MH and healthy fellow eyes were analyzed. The mean age was 64.9 years (range 47-81 years). The constant 'a' was significantly smaller in eyes with a MH than that of the fellow eyes (0.379 ± 0.094 vs 0.416 ± 0.121, P = 0.001, paired t test), indicating that the RA trajectory was wider in the MH eyes than in the fellow eyes. There was a significant correlation between the axial length and 'a' of the RA trajectory in the MH eyes (R = 0.273, P = 0.044) and in the fellow eyes (R = 0.356, P = 0.008; Spearman's rank correlation coefficient). CONCLUSIONS:Because eyes with a MH have a significantly wider and flatter RA trajectory, there may be greater traction on the fovea which is located between the RA arches. The causative role of this finding is still unclear.http://europepmc.org/articles/PMC4395100?pdf=render |
| spellingShingle | Naoya Yoshihara Taiji Sakamoto Takehiro Yamashita Toshifumi Yamashita Keita Yamakiri Shozo Sonoda Tatsuro Ishibashi Wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole. PLoS ONE |
| title | Wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole. |
| title_full | Wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole. |
| title_fullStr | Wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole. |
| title_full_unstemmed | Wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole. |
| title_short | Wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole. |
| title_sort | wider retinal artery trajectories in eyes with macular hole than in fellow eyes of patients with unilateral idiopathic macular hole |
| url | http://europepmc.org/articles/PMC4395100?pdf=render |
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