Genomic landscape of gliosarcoma: distinguishing features and targetable alterations

Genomic landscape of gliosarcoma: distinguishing features and targetable alterations

Abstract Gliosarcoma is an aggressive brain tumor with histologic features of glioblastoma (GBM) and soft tissue sarcoma. Despite its poor prognosis, its rarity has precluded analysis of its underlying biology. We used a multi-center database to characterize the genomic landscape of gliosarcoma. Seq...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Mark M. Zaki, Leila A. Mashouf, Eleanor Woodward, Pinky Langat, Saksham Gupta, Ian F. Dunn, Patrick Y. Wen, Brian V. Nahed, Wenya Linda Bi
Format:	Artykuł
Język:	English
Wydane:	Nature Portfolio 2021-09-01
Seria:	Scientific Reports
Dostęp online:	https://doi.org/10.1038/s41598-021-97454-6

Podobne zapisy

Infantile gliosarcoma Gliosarcoma infantil
od: José Roberto Tude Melo, i wsp.
Wydane: (2008-03-01)

Temporal gliosarcoma
od: Amit Agrawal, i wsp.
Wydane: (2015-03-01)

Recurrent Gliosarcoma in Pregnancy
od: İsmail Gülşen, i wsp.
Wydane: (2014-01-01)

Gliosarcoma: un tumor cerebral poco común (Gliosarcoma, a rare brain tumor)
od: Edison Vega, i wsp.
Wydane: (2014-08-01)

Secondary gliosarcoma: the clinicopathological features and the development of a patient-derived xenograft model of gliosarcoma
od: Karrie Mei-Yee Kiang, i wsp.
Wydane: (2021-03-01)

Gliosarcoma with Primary Skull Base Invasion
od: Quoc-Bao D. Nguyen, i wsp.
Wydane: (2016-01-01)

Gliosarcoma: The Distinct Genomic Alterations Identified by Comprehensive Analysis of Copy Number Variations
od: Chuan-dong Cheng, i wsp.
Wydane: (2022-01-01)

The Epigenomics of Pituitary Adenoma
od: Blake M. Hauser, i wsp.
Wydane: (2019-05-01)

Hypermutated phenotype in gliosarcoma of the spinal cord
od: Christopher S. Hong, i wsp.
Wydane: (2021-02-01)

Gliosarcoma: a study of four cases
od: Yildiz Güney, i wsp.
Wydane: (2010-06-01)

Gliosarcomas: magnetic resonance imaging findings
od: Aya FUKUDA, i wsp.
Wydane: (2020-02-01)

Integrated molecular and clinical analysis of BRAF-mutant glioma in adults
od: Karisa C. Schreck, i wsp.
Wydane: (2023-02-01)

Gliosarcoma of a Brain: A Challenging Diagnosis
od: Nornazirah Azizan, i wsp.
Wydane: (2020)

Gliosarcoma of a brain: a challenging diagnosis
od: Nornazirah Azizan, i wsp.
Wydane: (2020)

A case of right fronto-parietal gliosarcoma
od: Na Li, i wsp.
Wydane: (2025-02-01)

A rare, giant, lateral intraventricular gliosarcoma
od: Ho Xuan Tuan, MD, PhD, i wsp.
Wydane: (2023-01-01)

Campylobacteremia in stage IV gliosarcoma with bevacizumab treatment
od: Ping Liu
Wydane: (2012-04-01)

Primary gliosarcoma of the optic nerve – Case report
od: Rui Tuna, i wsp.
Wydane: (2020-06-01)

DTI-015 Produces Cures in T9 Gliosarcoma
od: Dennis Pietronigro, i wsp.
Wydane: (2003-01-01)

Malignant Pediatric Gliosarcoma Defies General Survival Data
od: Jovita Martin, i wsp.
Wydane: (2014-01-01)

Conditional survival and changing risk profile in patients with gliosarcoma
od: Lei Xu, i wsp.
Wydane: (2024-09-01)

Transformation of IDH-wildtype glioblastoma to gliosarcoma with features of osteosarcoma
od: Paweł Sobczyk, i wsp.
Wydane: (2024-03-01)

IDH1 mutant negative ganglioglioma progression to gliosarcoma
od: Liming Qiu, i wsp.
Wydane: (2017-09-01)

A case of recurrent gliosarcoma mimicking subdural hematoma
od: Ryan Khanna, MD, MSCI, i wsp.
Wydane: (2019-06-01)

A rare case of gliosarcoma after acute hemorrhage
od: Yunni Diansari, i wsp.
Wydane: (2019-01-01)

Pineal gliosarcoma in a 5-year-old girl
od: Ana María Granados, PhD, i wsp.
Wydane: (2018-02-01)

Computed Tomography, Magnetic Resonance Imaging, and Pathological Features of Gliosarcoma
od: Fan H, i wsp.
Wydane: (2022-11-01)

Primary gliosarcoma with widespread extracranial metastases—spatiotemporal morphological variation
od: Ming Luo, i wsp.
Wydane: (2022-08-01)

Multidisciplinary approaches to gliosarcoma: A case report and review of the literature
od: Collin M. Labak, i wsp.
Wydane: (2022-08-01)

Evaluating Surgical Resection Extent and Adjuvant Therapy in the Management of Gliosarcoma
od: Michael C. Jin, i wsp.
Wydane: (2020-03-01)

Extraneural metastatic gliosarcoma: A case report and review of the literature
od: Thara Tunthanathip, i wsp.
Wydane: (2020-01-01)

Pediatric gliosarcoma with fibrosarcomatous differentiation: Report of a rare case
od: Shantha Ravisankar, i wsp.
Wydane: (2012-01-01)

A 9L Gliosarcoma Transplantation Model for Studying Adoptive Immunotherapy into the Brains of Conscious Rats
od: Monika Fleshner, i wsp.
Wydane: (1992-07-01)

Gliosarcoma in a young patient with neurofibromatosis type 1. Case report
od: Luisa Fernanda Zúñiga-Cerón, i wsp.
Wydane: (2018-07-01)

Gliosarcoma: A Multi‐Institutional Analysis on Clinical Outcomes and Prognostic Factors
od: Siyer Roohani, i wsp.
Wydane: (2024-11-01)

Clinical Presentation, Approach and Outcome of Gliosarcoma: A Series of 12 Cases
od: Shreya Singh, i wsp.
Wydane: (2024-03-01)

Efficacy of 15 nm Gold Nanoparticles for Image-Guided Gliosarcoma Radiotherapy
od: Elette Engels, i wsp.
Wydane: (2023-10-01)

Gliosarcoma in a Paediatric Patient: A Rare Entity and Review of Literature
od: Meenakshi Shankar, i wsp.
Wydane: (2022-12-01)

Molecular Characterization of PDGFR-α/PDGF-A and c-KIT/SCF in Gliosarcomas
od: Rui M. Reis, i wsp.
Wydane: (2005-01-01)

Gliosarcoma in a patient with triple-negative breast cancer: A case report
od: Guojie Zhao, i wsp.
Wydane: (2023-01-01)