Genomic landscape of gliosarcoma: distinguishing features and targetable alterations

Abstract Gliosarcoma is an aggressive brain tumor with histologic features of glioblastoma (GBM) and soft tissue sarcoma. Despite its poor prognosis, its rarity has precluded analysis of its underlying biology. We used a multi-center database to characterize the genomic landscape of gliosarcoma. Seq...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Mark M. Zaki, Leila A. Mashouf, Eleanor Woodward, Pinky Langat, Saksham Gupta, Ian F. Dunn, Patrick Y. Wen, Brian V. Nahed, Wenya Linda Bi
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Nature Portfolio 2021-09-01
Cyfres:Scientific Reports
Mynediad Ar-lein:https://doi.org/10.1038/s41598-021-97454-6