Genomic landscape of gliosarcoma: distinguishing features and targetable alterations

Abstract Gliosarcoma is an aggressive brain tumor with histologic features of glioblastoma (GBM) and soft tissue sarcoma. Despite its poor prognosis, its rarity has precluded analysis of its underlying biology. We used a multi-center database to characterize the genomic landscape of gliosarcoma. Seq...

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Detalhes bibliográficos
Principais autores: Mark M. Zaki, Leila A. Mashouf, Eleanor Woodward, Pinky Langat, Saksham Gupta, Ian F. Dunn, Patrick Y. Wen, Brian V. Nahed, Wenya Linda Bi
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2021-09-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-021-97454-6