Genomic landscape of gliosarcoma: distinguishing features and targetable alterations

Abstract Gliosarcoma is an aggressive brain tumor with histologic features of glioblastoma (GBM) and soft tissue sarcoma. Despite its poor prognosis, its rarity has precluded analysis of its underlying biology. We used a multi-center database to characterize the genomic landscape of gliosarcoma. Seq...

Полное описание

Библиографические подробности
Главные авторы: Mark M. Zaki, Leila A. Mashouf, Eleanor Woodward, Pinky Langat, Saksham Gupta, Ian F. Dunn, Patrick Y. Wen, Brian V. Nahed, Wenya Linda Bi
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2021-09-01
Серии:Scientific Reports
Online-ссылка:https://doi.org/10.1038/s41598-021-97454-6