Electrically-switched differential microscopy based on computing liquid-crystal platforms
Detection of transparent phase specimens especially biological cells with desired contrasts is of great importance in visual display and medical diagnosis. Due to the pure-phase nature, conventional detection approaches may damage samples or require complex operations. Computing liquid crystal (LC)...
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Format: | Article |
Language: | English |
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De Gruyter
2024-01-01
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Series: | Nanophotonics |
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Online Access: | https://doi.org/10.1515/nanoph-2023-0688 |
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author | Liu Shuoqing Zheng Dandan Yang Qiang Chen Shizhen Wen Shuangchun Luo Hailu |
author_facet | Liu Shuoqing Zheng Dandan Yang Qiang Chen Shizhen Wen Shuangchun Luo Hailu |
author_sort | Liu Shuoqing |
collection | DOAJ |
description | Detection of transparent phase specimens especially biological cells with desired contrasts is of great importance in visual display and medical diagnosis. Due to the pure-phase nature, conventional detection approaches may damage samples or require complex operations. Computing liquid crystal (LC) is a thin and flat optical element with excellent capability in optical field modulation, which gives a feasible way to this issue from the perspective of analog optical computing. We here propose and experimentally implement an electrically switched two-dimensional (2D) differential microscopy based on computing LC platforms. The Pancharatnam–Berry phase LC polarization grating induces light’s spin separation to promote the 2D differential operation. Using the electrically tunable LC plate as the system phase retardance provider, the detecting mode can be flexibly switched from bright-field images to edge-enhanced images with desired contrasts. Remarkably, owing to the wavelength-independent feature closely related to the geometric phases, our proposed scheme is demonstrated to be applicable to the multi-wavelength microscopy imaging. These results open avenues to form real-time all-optical image processing and may facilitate multifunctional differential microscopy. |
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institution | Directory Open Access Journal |
issn | 2192-8614 |
language | English |
last_indexed | 2024-04-24T22:52:46Z |
publishDate | 2024-01-01 |
publisher | De Gruyter |
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series | Nanophotonics |
spelling | doaj.art-96cfaff9351d42cfb703eb0087c37aaa2024-03-18T10:28:06ZengDe GruyterNanophotonics2192-86142024-01-0113332733810.1515/nanoph-2023-0688Electrically-switched differential microscopy based on computing liquid-crystal platformsLiu Shuoqing0Zheng Dandan1Yang Qiang2Chen Shizhen3Wen Shuangchun4Luo Hailu5Key Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaDetection of transparent phase specimens especially biological cells with desired contrasts is of great importance in visual display and medical diagnosis. Due to the pure-phase nature, conventional detection approaches may damage samples or require complex operations. Computing liquid crystal (LC) is a thin and flat optical element with excellent capability in optical field modulation, which gives a feasible way to this issue from the perspective of analog optical computing. We here propose and experimentally implement an electrically switched two-dimensional (2D) differential microscopy based on computing LC platforms. The Pancharatnam–Berry phase LC polarization grating induces light’s spin separation to promote the 2D differential operation. Using the electrically tunable LC plate as the system phase retardance provider, the detecting mode can be flexibly switched from bright-field images to edge-enhanced images with desired contrasts. Remarkably, owing to the wavelength-independent feature closely related to the geometric phases, our proposed scheme is demonstrated to be applicable to the multi-wavelength microscopy imaging. These results open avenues to form real-time all-optical image processing and may facilitate multifunctional differential microscopy.https://doi.org/10.1515/nanoph-2023-0688computing liquid-crystalall-optical image processingoptical differential operationedge-enhanced imagingmicroscopy imaging |
spellingShingle | Liu Shuoqing Zheng Dandan Yang Qiang Chen Shizhen Wen Shuangchun Luo Hailu Electrically-switched differential microscopy based on computing liquid-crystal platforms Nanophotonics computing liquid-crystal all-optical image processing optical differential operation edge-enhanced imaging microscopy imaging |
title | Electrically-switched differential microscopy based on computing liquid-crystal platforms |
title_full | Electrically-switched differential microscopy based on computing liquid-crystal platforms |
title_fullStr | Electrically-switched differential microscopy based on computing liquid-crystal platforms |
title_full_unstemmed | Electrically-switched differential microscopy based on computing liquid-crystal platforms |
title_short | Electrically-switched differential microscopy based on computing liquid-crystal platforms |
title_sort | electrically switched differential microscopy based on computing liquid crystal platforms |
topic | computing liquid-crystal all-optical image processing optical differential operation edge-enhanced imaging microscopy imaging |
url | https://doi.org/10.1515/nanoph-2023-0688 |
work_keys_str_mv | AT liushuoqing electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms AT zhengdandan electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms AT yangqiang electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms AT chenshizhen electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms AT wenshuangchun electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms AT luohailu electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms |