Electrically-switched differential microscopy based on computing liquid-crystal platforms

Detection of transparent phase specimens especially biological cells with desired contrasts is of great importance in visual display and medical diagnosis. Due to the pure-phase nature, conventional detection approaches may damage samples or require complex operations. Computing liquid crystal (LC)...

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Main Authors: Liu Shuoqing, Zheng Dandan, Yang Qiang, Chen Shizhen, Wen Shuangchun, Luo Hailu
Format: Article
Language:English
Published: De Gruyter 2024-01-01
Series:Nanophotonics
Subjects:
Online Access:https://doi.org/10.1515/nanoph-2023-0688
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author Liu Shuoqing
Zheng Dandan
Yang Qiang
Chen Shizhen
Wen Shuangchun
Luo Hailu
author_facet Liu Shuoqing
Zheng Dandan
Yang Qiang
Chen Shizhen
Wen Shuangchun
Luo Hailu
author_sort Liu Shuoqing
collection DOAJ
description Detection of transparent phase specimens especially biological cells with desired contrasts is of great importance in visual display and medical diagnosis. Due to the pure-phase nature, conventional detection approaches may damage samples or require complex operations. Computing liquid crystal (LC) is a thin and flat optical element with excellent capability in optical field modulation, which gives a feasible way to this issue from the perspective of analog optical computing. We here propose and experimentally implement an electrically switched two-dimensional (2D) differential microscopy based on computing LC platforms. The Pancharatnam–Berry phase LC polarization grating induces light’s spin separation to promote the 2D differential operation. Using the electrically tunable LC plate as the system phase retardance provider, the detecting mode can be flexibly switched from bright-field images to edge-enhanced images with desired contrasts. Remarkably, owing to the wavelength-independent feature closely related to the geometric phases, our proposed scheme is demonstrated to be applicable to the multi-wavelength microscopy imaging. These results open avenues to form real-time all-optical image processing and may facilitate multifunctional differential microscopy.
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spelling doaj.art-96cfaff9351d42cfb703eb0087c37aaa2024-03-18T10:28:06ZengDe GruyterNanophotonics2192-86142024-01-0113332733810.1515/nanoph-2023-0688Electrically-switched differential microscopy based on computing liquid-crystal platformsLiu Shuoqing0Zheng Dandan1Yang Qiang2Chen Shizhen3Wen Shuangchun4Luo Hailu5Key Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaKey Laboratory of Micro-/Nano-Optoelectronic Devices of Ministry of Education and Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices, School of Physics and Electronics, Hunan University, Changsha410082, ChinaDetection of transparent phase specimens especially biological cells with desired contrasts is of great importance in visual display and medical diagnosis. Due to the pure-phase nature, conventional detection approaches may damage samples or require complex operations. Computing liquid crystal (LC) is a thin and flat optical element with excellent capability in optical field modulation, which gives a feasible way to this issue from the perspective of analog optical computing. We here propose and experimentally implement an electrically switched two-dimensional (2D) differential microscopy based on computing LC platforms. The Pancharatnam–Berry phase LC polarization grating induces light’s spin separation to promote the 2D differential operation. Using the electrically tunable LC plate as the system phase retardance provider, the detecting mode can be flexibly switched from bright-field images to edge-enhanced images with desired contrasts. Remarkably, owing to the wavelength-independent feature closely related to the geometric phases, our proposed scheme is demonstrated to be applicable to the multi-wavelength microscopy imaging. These results open avenues to form real-time all-optical image processing and may facilitate multifunctional differential microscopy.https://doi.org/10.1515/nanoph-2023-0688computing liquid-crystalall-optical image processingoptical differential operationedge-enhanced imagingmicroscopy imaging
spellingShingle Liu Shuoqing
Zheng Dandan
Yang Qiang
Chen Shizhen
Wen Shuangchun
Luo Hailu
Electrically-switched differential microscopy based on computing liquid-crystal platforms
Nanophotonics
computing liquid-crystal
all-optical image processing
optical differential operation
edge-enhanced imaging
microscopy imaging
title Electrically-switched differential microscopy based on computing liquid-crystal platforms
title_full Electrically-switched differential microscopy based on computing liquid-crystal platforms
title_fullStr Electrically-switched differential microscopy based on computing liquid-crystal platforms
title_full_unstemmed Electrically-switched differential microscopy based on computing liquid-crystal platforms
title_short Electrically-switched differential microscopy based on computing liquid-crystal platforms
title_sort electrically switched differential microscopy based on computing liquid crystal platforms
topic computing liquid-crystal
all-optical image processing
optical differential operation
edge-enhanced imaging
microscopy imaging
url https://doi.org/10.1515/nanoph-2023-0688
work_keys_str_mv AT liushuoqing electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms
AT zhengdandan electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms
AT yangqiang electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms
AT chenshizhen electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms
AT wenshuangchun electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms
AT luohailu electricallyswitcheddifferentialmicroscopybasedoncomputingliquidcrystalplatforms