Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic model
Background: Rotavirus infection is a major cause of childhood diarrhea in Libya. The objective of this study is to evaluate the cost-effectiveness of rotavirus vaccination in that country. Methods: We used a published decision tree model that has been adapted to the Libyan situation to analyze a bir...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2014-12-01
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| Series: | Libyan Journal of Medicine |
| Subjects: | |
| Online Access: | http://www.libyanjournalofmedicine.net/index.php/ljm/article/download/26236/pdf_1 |
| _version_ | 1817970458092371968 |
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| author | Salem Alkoshi Namaitijiang Maimaiti Maznah Dahlui |
| author_facet | Salem Alkoshi Namaitijiang Maimaiti Maznah Dahlui |
| author_sort | Salem Alkoshi |
| collection | DOAJ |
| description | Background: Rotavirus infection is a major cause of childhood diarrhea in Libya. The objective of this study is to evaluate the cost-effectiveness of rotavirus vaccination in that country. Methods: We used a published decision tree model that has been adapted to the Libyan situation to analyze a birth cohort of 160,000 children. The evaluation of diarrhea events in three public hospitals helped to estimate the rotavirus burden. The economic analysis was done from two perspectives: health care provider and societal. Univariate sensitivity analyses were conducted to assess uncertainty in some values of the variables selected. Results: The three hospitals received 545 diarrhea patients aged≤5 with 311 (57%) rotavirus positive test results during a 9-month period. The societal cost for treatment of a case of rotavirus diarrhea was estimated at US$ 661/event. The incremental cost-effectiveness ratio with a vaccine price of US$ 27 per course was US$ 8,972 per quality-adjusted life year gained from the health care perspective. From a societal perspective, the analysis shows cost savings of around US$ 16 per child. Conclusion: The model shows that rotavirus vaccination could be economically a very attractive intervention in Libya. |
| first_indexed | 2024-04-13T20:34:17Z |
| format | Article |
| id | doaj.art-96d25229dcfb4ceca241a53b188e2635 |
| institution | Directory Open Access Journal |
| issn | 1819-6357 |
| language | English |
| last_indexed | 2024-04-13T20:34:17Z |
| publishDate | 2014-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Libyan Journal of Medicine |
| spelling | doaj.art-96d25229dcfb4ceca241a53b188e26352022-12-22T02:31:04ZengTaylor & Francis GroupLibyan Journal of Medicine1819-63572014-12-01901910.3402/ljm.v9.2623626236Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic modelSalem Alkoshi0Namaitijiang Maimaiti1Maznah Dahlui2 Julius Centre, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia International Institute for Global Health, United Nations University, Kuala Lumpur, Malaysia Julius Centre, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, MalaysiaBackground: Rotavirus infection is a major cause of childhood diarrhea in Libya. The objective of this study is to evaluate the cost-effectiveness of rotavirus vaccination in that country. Methods: We used a published decision tree model that has been adapted to the Libyan situation to analyze a birth cohort of 160,000 children. The evaluation of diarrhea events in three public hospitals helped to estimate the rotavirus burden. The economic analysis was done from two perspectives: health care provider and societal. Univariate sensitivity analyses were conducted to assess uncertainty in some values of the variables selected. Results: The three hospitals received 545 diarrhea patients aged≤5 with 311 (57%) rotavirus positive test results during a 9-month period. The societal cost for treatment of a case of rotavirus diarrhea was estimated at US$ 661/event. The incremental cost-effectiveness ratio with a vaccine price of US$ 27 per course was US$ 8,972 per quality-adjusted life year gained from the health care perspective. From a societal perspective, the analysis shows cost savings of around US$ 16 per child. Conclusion: The model shows that rotavirus vaccination could be economically a very attractive intervention in Libya.http://www.libyanjournalofmedicine.net/index.php/ljm/article/download/26236/pdf_1diarrhearotaviruscost-effectivenessvaccinationLibya |
| spellingShingle | Salem Alkoshi Namaitijiang Maimaiti Maznah Dahlui Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic model Libyan Journal of Medicine diarrhea rotavirus cost-effectiveness vaccination Libya |
| title | Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic model |
| title_full | Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic model |
| title_fullStr | Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic model |
| title_full_unstemmed | Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic model |
| title_short | Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic model |
| title_sort | cost effectiveness analysis of rotavirus vaccination among libyan children using a simple economic model |
| topic | diarrhea rotavirus cost-effectiveness vaccination Libya |
| url | http://www.libyanjournalofmedicine.net/index.php/ljm/article/download/26236/pdf_1 |
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