Chain-End Modifications and Sequence Arrangements of Antimicrobial Peptoids for Mediating Activity and Nano-Assembly

Chain-End Modifications and Sequence Arrangements of Antimicrobial Peptoids for Mediating Activity and Nano-Assembly

Poly(N-substituted glycine) “peptoids” are an interesting class of peptidomimics that can resist proteolysis and mimic naturally found antimicrobial peptides (AMPs), which exhibit wide spectrum activity against bacteria. This work investigates the possibility of modifying peptoid AMP mimics (AMPMs)...

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Bibliographic Details
Main Authors: Abshar Hasan, Varun Saxena, Valeria Castelletto, Georgina Zimbitas, Jani Seitsonen, Janne Ruokolainen, Lalit M. Pandey, Jan Sefcik, Ian W. Hamley, King Hang Aaron Lau
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Chemistry
Subjects:
self-assembly
micelles
antimicrobial peptide
peptoids
DLS
CAC
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00416/full

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