Common food allergens and their IgE-binding epitopes
Food allergy is an adverse immune response to certain kinds of food. Although any food can cause allergic reactions, chicken egg, cow's milk, wheat, shellfish, fruit, and buckwheat account for 75% of food allergies in Japan. Allergen-specific immunoglobulin E (IgE) antibodies play a pivotal rol...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2015-10-01
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| Series: | Allergology International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S132389301500146X |
| _version_ | 1819093098763911168 |
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| author | Hiroaki Matsuo Tomoharu Yokooji Takanori Taogoshi |
| author_facet | Hiroaki Matsuo Tomoharu Yokooji Takanori Taogoshi |
| author_sort | Hiroaki Matsuo |
| collection | DOAJ |
| description | Food allergy is an adverse immune response to certain kinds of food. Although any food can cause allergic reactions, chicken egg, cow's milk, wheat, shellfish, fruit, and buckwheat account for 75% of food allergies in Japan. Allergen-specific immunoglobulin E (IgE) antibodies play a pivotal role in the development of food allergy. Recent advances in molecular biological techniques have enabled the efficient analysis of food allergens. As a result, many food allergens have been identified, and their molecular structure and IgE-binding epitopes have also been identified. Studies of allergens have demonstrated that IgE antibodies specific to allergen components and/or the peptide epitopes are good indicators for the identification of patients with food allergy, prediction of clinical severity and development of tolerance. In this review, we summarize our current knowledge regarding the allergens and IgE epitopes in the well-researched allergies to chicken egg, cow's milk, wheat, shrimp, and peanut. |
| first_indexed | 2024-12-21T23:06:07Z |
| format | Article |
| id | doaj.art-96d5ba6cf24445ffa4208308624e23ee |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-12-21T23:06:07Z |
| publishDate | 2015-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-96d5ba6cf24445ffa4208308624e23ee2022-12-21T18:47:09ZengElsevierAllergology International1323-89302015-10-0164433234310.1016/j.alit.2015.06.009Common food allergens and their IgE-binding epitopesHiroaki Matsuo0Tomoharu Yokooji1Takanori Taogoshi2Department of Pharmaceutical Services, Hiroshima University Hospital, Hiroshima, JapanDepartment of Pathophysiology and Therapeutics, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, JapanDepartment of Pharmaceutical Services, Hiroshima University Hospital, Hiroshima, JapanFood allergy is an adverse immune response to certain kinds of food. Although any food can cause allergic reactions, chicken egg, cow's milk, wheat, shellfish, fruit, and buckwheat account for 75% of food allergies in Japan. Allergen-specific immunoglobulin E (IgE) antibodies play a pivotal role in the development of food allergy. Recent advances in molecular biological techniques have enabled the efficient analysis of food allergens. As a result, many food allergens have been identified, and their molecular structure and IgE-binding epitopes have also been identified. Studies of allergens have demonstrated that IgE antibodies specific to allergen components and/or the peptide epitopes are good indicators for the identification of patients with food allergy, prediction of clinical severity and development of tolerance. In this review, we summarize our current knowledge regarding the allergens and IgE epitopes in the well-researched allergies to chicken egg, cow's milk, wheat, shrimp, and peanut.http://www.sciencedirect.com/science/article/pii/S132389301500146XAllergenDiagnosisEpitopeFood allergyImmunoglobulin E |
| spellingShingle | Hiroaki Matsuo Tomoharu Yokooji Takanori Taogoshi Common food allergens and their IgE-binding epitopes Allergology International Allergen Diagnosis Epitope Food allergy Immunoglobulin E |
| title | Common food allergens and their IgE-binding epitopes |
| title_full | Common food allergens and their IgE-binding epitopes |
| title_fullStr | Common food allergens and their IgE-binding epitopes |
| title_full_unstemmed | Common food allergens and their IgE-binding epitopes |
| title_short | Common food allergens and their IgE-binding epitopes |
| title_sort | common food allergens and their ige binding epitopes |
| topic | Allergen Diagnosis Epitope Food allergy Immunoglobulin E |
| url | http://www.sciencedirect.com/science/article/pii/S132389301500146X |
| work_keys_str_mv | AT hiroakimatsuo commonfoodallergensandtheirigebindingepitopes AT tomoharuyokooji commonfoodallergensandtheirigebindingepitopes AT takanoritaogoshi commonfoodallergensandtheirigebindingepitopes |