Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores

Abstract Objective To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). Methods This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical...

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Main Authors: Mateus Kenji Christo Miyahira, João Victor Novaretti, Diego Costa Astur, Camila Cohen Kaleka, Joicemar Tarouco Amaro, Moisés Cohen
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2021-08-01
Series:Revista Brasileira de Ortopedia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162021000300333&tlng=pt
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author Mateus Kenji Christo Miyahira
João Victor Novaretti
Diego Costa Astur
Camila Cohen Kaleka
Joicemar Tarouco Amaro
Moisés Cohen
author_facet Mateus Kenji Christo Miyahira
João Victor Novaretti
Diego Costa Astur
Camila Cohen Kaleka
Joicemar Tarouco Amaro
Moisés Cohen
author_sort Mateus Kenji Christo Miyahira
collection DOAJ
description Abstract Objective To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). Methods This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical evaluation was made by comparing the Lysholm and International Knee Document Commitee (IKDC) scores in the pre- and postoperative period of 12 months, and radiological evaluation using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score in the same postoperative period. Results The mean age of the patients was 39.2 years old, and the mean size of the chondral lesions was 1.55cm2. There was a significant improvement in clinical scores, with a mean increase of 24.6 points on Lysholm and of 24.3 on IKDC after 12 months. In the radiological evaluation, MOCART had a mean of 65 points. It was observed that the larger the size of the lesion, the greater the improvement in scores. Conclusion Evaluating subjective clinical scores, the treatment of chondral lesions with the collagen membrane showed good results, as well as the evaluation of MOCART, with greater benefit in larger lesions.
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spelling doaj.art-96d7fdd0e28a44c1afe0983e97c10a4c2024-04-03T08:58:25ZengThieme Revinter Publicações Ltda.Revista Brasileira de Ortopedia1982-43782021-08-0156333333910.1055/s-0040-1712493Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical ScoresMateus Kenji Christo Miyahirahttps://orcid.org/0000-0001-5305-7957João Victor Novarettihttps://orcid.org/0000-0002-8168-3469Diego Costa Asturhttps://orcid.org/0000-0001-9163-7979Camila Cohen KalekaJoicemar Tarouco AmaroMoisés CohenAbstract Objective To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). Methods This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical evaluation was made by comparing the Lysholm and International Knee Document Commitee (IKDC) scores in the pre- and postoperative period of 12 months, and radiological evaluation using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score in the same postoperative period. Results The mean age of the patients was 39.2 years old, and the mean size of the chondral lesions was 1.55cm2. There was a significant improvement in clinical scores, with a mean increase of 24.6 points on Lysholm and of 24.3 on IKDC after 12 months. In the radiological evaluation, MOCART had a mean of 65 points. It was observed that the larger the size of the lesion, the greater the improvement in scores. Conclusion Evaluating subjective clinical scores, the treatment of chondral lesions with the collagen membrane showed good results, as well as the evaluation of MOCART, with greater benefit in larger lesions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162021000300333&tlng=ptarticular cartilagechondrogenesiscollagenknee injuries
spellingShingle Mateus Kenji Christo Miyahira
João Victor Novaretti
Diego Costa Astur
Camila Cohen Kaleka
Joicemar Tarouco Amaro
Moisés Cohen
Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores
Revista Brasileira de Ortopedia
articular cartilage
chondrogenesis
collagen
knee injuries
title Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores
title_full Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores
title_fullStr Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores
title_full_unstemmed Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores
title_short Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores
title_sort larger chondral lesions treated with collagen membrane matrix induced autologous chondrogenesis show larger increase in clinical scores
topic articular cartilage
chondrogenesis
collagen
knee injuries
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162021000300333&tlng=pt
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