Resistance in the Genus <i>Spodoptera</i>: Key Insect Detoxification Genes
The genus <i>Spodoptera</i> (Lepidoptera: Noctuidae) includes species that are among the most important crop pests in the world. These polyphagous species are able to feed on many plants, including corn, rice and cotton. In addition to their ability to adapt to toxic compounds produced b...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Insects |
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| Online Access: | https://www.mdpi.com/2075-4450/12/6/544 |
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| author | Frédérique Hilliou Thomas Chertemps Martine Maïbèche Gaëlle Le Goff |
| author_facet | Frédérique Hilliou Thomas Chertemps Martine Maïbèche Gaëlle Le Goff |
| author_sort | Frédérique Hilliou |
| collection | DOAJ |
| description | The genus <i>Spodoptera</i> (Lepidoptera: Noctuidae) includes species that are among the most important crop pests in the world. These polyphagous species are able to feed on many plants, including corn, rice and cotton. In addition to their ability to adapt to toxic compounds produced by plants, they have developed resistance to the chemical insecticides used for their control. One of the main mechanisms developed by insects to become resistant involves detoxification enzymes. In this review, we illustrate some examples of the role of major families of detoxification enzymes such as cytochromes P450, carboxyl/cholinesterases, glutathione S-transferases (GST) and transporters such as ATP-binding cassette (ABC) transporters in insecticide resistance. We compare available data for four species, <i>Spodoptera exigua</i>, <i>S. frugiperda</i>, <i>S. littoralis</i> and <i>S. litura</i>. Molecular mechanisms underlying the involvement of these genes in resistance will be described, including the duplication of the CYP9A cluster, over-expression of GST epsilon or point mutations in acetylcholinesterase and ABCC2. This review is not intended to be exhaustive but to highlight the key roles of certain genes. |
| first_indexed | 2024-03-10T10:30:25Z |
| format | Article |
| id | doaj.art-96e2eeda447d4ca98598f02dd327fd42 |
| institution | Directory Open Access Journal |
| issn | 2075-4450 |
| language | English |
| last_indexed | 2024-03-10T10:30:25Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Insects |
| spelling | doaj.art-96e2eeda447d4ca98598f02dd327fd422023-11-21T23:41:49ZengMDPI AGInsects2075-44502021-06-0112654410.3390/insects12060544Resistance in the Genus <i>Spodoptera</i>: Key Insect Detoxification GenesFrédérique Hilliou0Thomas Chertemps1Martine Maïbèche2Gaëlle Le Goff3Université Côte D’Azur, INRAE, CNRS, ISA, F-06903 Sophia Antipolis, FranceInstitut D’Ecologie et des Sciences de L’Environnement de Paris, Sorbonne Université, CNRS, INRAE, IRD, iEES-Paris, F-75005 Paris, FranceInstitut D’Ecologie et des Sciences de L’Environnement de Paris, Sorbonne Université, CNRS, INRAE, IRD, iEES-Paris, F-75005 Paris, FranceUniversité Côte D’Azur, INRAE, CNRS, ISA, F-06903 Sophia Antipolis, FranceThe genus <i>Spodoptera</i> (Lepidoptera: Noctuidae) includes species that are among the most important crop pests in the world. These polyphagous species are able to feed on many plants, including corn, rice and cotton. In addition to their ability to adapt to toxic compounds produced by plants, they have developed resistance to the chemical insecticides used for their control. One of the main mechanisms developed by insects to become resistant involves detoxification enzymes. In this review, we illustrate some examples of the role of major families of detoxification enzymes such as cytochromes P450, carboxyl/cholinesterases, glutathione S-transferases (GST) and transporters such as ATP-binding cassette (ABC) transporters in insecticide resistance. We compare available data for four species, <i>Spodoptera exigua</i>, <i>S. frugiperda</i>, <i>S. littoralis</i> and <i>S. litura</i>. Molecular mechanisms underlying the involvement of these genes in resistance will be described, including the duplication of the CYP9A cluster, over-expression of GST epsilon or point mutations in acetylcholinesterase and ABCC2. This review is not intended to be exhaustive but to highlight the key roles of certain genes.https://www.mdpi.com/2075-4450/12/6/544resistance<i>Spodoptera</i>cytochromes P450carboxyl/cholinesterasesglutathione S-transferasesATP-binding cassette transporters |
| spellingShingle | Frédérique Hilliou Thomas Chertemps Martine Maïbèche Gaëlle Le Goff Resistance in the Genus <i>Spodoptera</i>: Key Insect Detoxification Genes Insects resistance <i>Spodoptera</i> cytochromes P450 carboxyl/cholinesterases glutathione S-transferases ATP-binding cassette transporters |
| title | Resistance in the Genus <i>Spodoptera</i>: Key Insect Detoxification Genes |
| title_full | Resistance in the Genus <i>Spodoptera</i>: Key Insect Detoxification Genes |
| title_fullStr | Resistance in the Genus <i>Spodoptera</i>: Key Insect Detoxification Genes |
| title_full_unstemmed | Resistance in the Genus <i>Spodoptera</i>: Key Insect Detoxification Genes |
| title_short | Resistance in the Genus <i>Spodoptera</i>: Key Insect Detoxification Genes |
| title_sort | resistance in the genus i spodoptera i key insect detoxification genes |
| topic | resistance <i>Spodoptera</i> cytochromes P450 carboxyl/cholinesterases glutathione S-transferases ATP-binding cassette transporters |
| url | https://www.mdpi.com/2075-4450/12/6/544 |
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