Pharmacological effects of baicalin in lung diseases
The flavonoids baicalin and baicalein were discovered in the root of Scutellaria baicalensis Georgi and are primarily used in traditional Chinese medicine, herbal supplements and healthcare. Recently, accumulated investigations have demonstrated the therapeutic benefits of baicalin in treating vario...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-04-01
|
| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1188202/full |
| _version_ | 1797840551580532736 |
|---|---|
| author | Duoning Wang Duoning Wang Yi Li |
| author_facet | Duoning Wang Duoning Wang Yi Li |
| author_sort | Duoning Wang |
| collection | DOAJ |
| description | The flavonoids baicalin and baicalein were discovered in the root of Scutellaria baicalensis Georgi and are primarily used in traditional Chinese medicine, herbal supplements and healthcare. Recently, accumulated investigations have demonstrated the therapeutic benefits of baicalin in treating various lung diseases due to its antioxidant, anti-inflammatory, immunomodulatory, antiapoptotic, anticancer, and antiviral effects. In this review, the PubMed database and ClinicalTrials website were searched with the search string “baicalin” and “lung” for articles published between September 1970 and March 2023. We summarized the therapeutic role that baicalin plays in a variety of lung diseases, such as chronic obstructive pulmonary disease, asthma, pulmonary fibrosis, pulmonary hypertension, pulmonary infections, acute lung injury/acute respiratory distress syndrome, and lung cancer. We also discussed the underlying mechanisms of baicalin targeting in these lung diseases. |
| first_indexed | 2024-04-09T16:17:12Z |
| format | Article |
| id | doaj.art-96e5fe8526b049f98e4a8a2eeec93541 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-09T16:17:12Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-96e5fe8526b049f98e4a8a2eeec935412023-04-24T04:15:42ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-04-011410.3389/fphar.2023.11882021188202Pharmacological effects of baicalin in lung diseasesDuoning Wang0Duoning Wang1Yi Li2Chengdu Hi-tech Nanxili Jiuzheng Clinic, Chengdu, Sichuan, ChinaChengdu Hi-tech Nanxili Jiuzheng Clinic, Chengdu, Sichuan, ChinaChengdu Hi-tech Nanxili Jiuzheng Clinic, Chengdu, Sichuan, ChinaThe flavonoids baicalin and baicalein were discovered in the root of Scutellaria baicalensis Georgi and are primarily used in traditional Chinese medicine, herbal supplements and healthcare. Recently, accumulated investigations have demonstrated the therapeutic benefits of baicalin in treating various lung diseases due to its antioxidant, anti-inflammatory, immunomodulatory, antiapoptotic, anticancer, and antiviral effects. In this review, the PubMed database and ClinicalTrials website were searched with the search string “baicalin” and “lung” for articles published between September 1970 and March 2023. We summarized the therapeutic role that baicalin plays in a variety of lung diseases, such as chronic obstructive pulmonary disease, asthma, pulmonary fibrosis, pulmonary hypertension, pulmonary infections, acute lung injury/acute respiratory distress syndrome, and lung cancer. We also discussed the underlying mechanisms of baicalin targeting in these lung diseases.https://www.frontiersin.org/articles/10.3389/fphar.2023.1188202/fullbaicalinlung diseaselung infectionlung injurylung cancer |
| spellingShingle | Duoning Wang Duoning Wang Yi Li Pharmacological effects of baicalin in lung diseases Frontiers in Pharmacology baicalin lung disease lung infection lung injury lung cancer |
| title | Pharmacological effects of baicalin in lung diseases |
| title_full | Pharmacological effects of baicalin in lung diseases |
| title_fullStr | Pharmacological effects of baicalin in lung diseases |
| title_full_unstemmed | Pharmacological effects of baicalin in lung diseases |
| title_short | Pharmacological effects of baicalin in lung diseases |
| title_sort | pharmacological effects of baicalin in lung diseases |
| topic | baicalin lung disease lung infection lung injury lung cancer |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1188202/full |
| work_keys_str_mv | AT duoningwang pharmacologicaleffectsofbaicalininlungdiseases AT duoningwang pharmacologicaleffectsofbaicalininlungdiseases AT yili pharmacologicaleffectsofbaicalininlungdiseases |