Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies
Abundant immunological assays currently exist for detecting pathogens and identifying infected individuals, making detection of diseases at early stages integral to preventing their spread, together with the consequent emergence of global health crises. Lateral flow immunoassay (LFIA) is a test char...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
|
| Series: | Micromachines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-666X/13/11/1901 |
| _version_ | 1797467190733045760 |
|---|---|
| author | Rowa Y. Alhabbab |
| author_facet | Rowa Y. Alhabbab |
| author_sort | Rowa Y. Alhabbab |
| collection | DOAJ |
| description | Abundant immunological assays currently exist for detecting pathogens and identifying infected individuals, making detection of diseases at early stages integral to preventing their spread, together with the consequent emergence of global health crises. Lateral flow immunoassay (LFIA) is a test characterized by simplicity, low cost, and quick results. Furthermore, LFIA testing does not need well-trained individuals or laboratory settings. Therefore, it has been serving as an attractive tool that has been extensively used during the ongoing COVID-19 pandemic. Here, the LFIA strip’s available formats, reporter systems, components, and preparation are discussed. Moreover, this review provides an overview of the current LFIAs in detecting infectious viral antigens and humoral responses to viral infections. |
| first_indexed | 2024-03-09T18:50:07Z |
| format | Article |
| id | doaj.art-96e7c08be0d24ca5bc4b0e86d485912f |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-09T18:50:07Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-96e7c08be0d24ca5bc4b0e86d485912f2023-11-24T05:54:57ZengMDPI AGMicromachines2072-666X2022-11-011311190110.3390/mi13111901Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and AntibodiesRowa Y. Alhabbab0Vaccines and Immunotherapy Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi ArabiaAbundant immunological assays currently exist for detecting pathogens and identifying infected individuals, making detection of diseases at early stages integral to preventing their spread, together with the consequent emergence of global health crises. Lateral flow immunoassay (LFIA) is a test characterized by simplicity, low cost, and quick results. Furthermore, LFIA testing does not need well-trained individuals or laboratory settings. Therefore, it has been serving as an attractive tool that has been extensively used during the ongoing COVID-19 pandemic. Here, the LFIA strip’s available formats, reporter systems, components, and preparation are discussed. Moreover, this review provides an overview of the current LFIAs in detecting infectious viral antigens and humoral responses to viral infections.https://www.mdpi.com/2072-666X/13/11/1901lateral flow immunoassayviral infectionsdiagnostic toolantigen detectionantibodies detection |
| spellingShingle | Rowa Y. Alhabbab Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies Micromachines lateral flow immunoassay viral infections diagnostic tool antigen detection antibodies detection |
| title | Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies |
| title_full | Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies |
| title_fullStr | Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies |
| title_full_unstemmed | Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies |
| title_short | Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies |
| title_sort | lateral flow immunoassays for detecting viral infectious antigens and antibodies |
| topic | lateral flow immunoassay viral infections diagnostic tool antigen detection antibodies detection |
| url | https://www.mdpi.com/2072-666X/13/11/1901 |
| work_keys_str_mv | AT rowayalhabbab lateralflowimmunoassaysfordetectingviralinfectiousantigensandantibodies |