A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction

A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction

<p>Abstract</p> <p>Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry. As the CXCR4 binding site is not exposed until CD134-binding ha...

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Bibliographic Details
Main Authors: Samman Ayman, Logan Nicola, McMonagle Elizabeth L, Willett Brian J, Hosie Margaret J
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/77

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