Deep Sea Actinomycetes and Their Secondary Metabolites
Deep sea is a unique and extreme environment. It is a hot spot for hunting marine actinomycetes resources and secondary metabolites. The novel deep sea actinomycete species reported from 2006 to 2016 including 21 species under 13 genera with the maximum number from Microbacterium, followed by Dermac...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-05-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fmicb.2017.00760/full |
| _version_ | 1830515927841505280 |
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| author | Kui Hong Manita Kamjam Periyasamy Sivalingam Zinxin Deng |
| author_facet | Kui Hong Manita Kamjam Periyasamy Sivalingam Zinxin Deng |
| author_sort | Kui Hong |
| collection | DOAJ |
| description | Deep sea is a unique and extreme environment. It is a hot spot for hunting marine actinomycetes resources and secondary metabolites. The novel deep sea actinomycete species reported from 2006 to 2016 including 21 species under 13 genera with the maximum number from Microbacterium, followed by Dermacoccus, Streptomyces and Verrucosispora, and one novel species for the other 9 genera. Eight genera of actinomycetes were reported to produce secondary metabolites, among which Streptomyces is the richest producer. Most of the compounds produced by the deep sea actinomycetes presented antimicrobial and anti-cancer cell activities. Gene clusters related to biosynthesis of desotamide, heronamide, and lobophorin have been identified from the deep sea derived Streptomyces. |
| first_indexed | 2024-12-22T03:31:57Z |
| format | Article |
| id | doaj.art-96ef8bf38d3440abaf1d2360bd7d652b |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-22T03:31:57Z |
| publishDate | 2017-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-96ef8bf38d3440abaf1d2360bd7d652b2022-12-21T18:40:28ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2017-05-01810.3389/fmicb.2017.00760251567Deep Sea Actinomycetes and Their Secondary MetabolitesKui HongManita KamjamPeriyasamy SivalingamZinxin DengDeep sea is a unique and extreme environment. It is a hot spot for hunting marine actinomycetes resources and secondary metabolites. The novel deep sea actinomycete species reported from 2006 to 2016 including 21 species under 13 genera with the maximum number from Microbacterium, followed by Dermacoccus, Streptomyces and Verrucosispora, and one novel species for the other 9 genera. Eight genera of actinomycetes were reported to produce secondary metabolites, among which Streptomyces is the richest producer. Most of the compounds produced by the deep sea actinomycetes presented antimicrobial and anti-cancer cell activities. Gene clusters related to biosynthesis of desotamide, heronamide, and lobophorin have been identified from the deep sea derived Streptomyces.http://journal.frontiersin.org/article/10.3389/fmicb.2017.00760/fulldeep seaactinomycetesbioactive natural productsbiosynthesisnovel species |
| spellingShingle | Kui Hong Manita Kamjam Periyasamy Sivalingam Zinxin Deng Deep Sea Actinomycetes and Their Secondary Metabolites Frontiers in Microbiology deep sea actinomycetes bioactive natural products biosynthesis novel species |
| title | Deep Sea Actinomycetes and Their Secondary Metabolites |
| title_full | Deep Sea Actinomycetes and Their Secondary Metabolites |
| title_fullStr | Deep Sea Actinomycetes and Their Secondary Metabolites |
| title_full_unstemmed | Deep Sea Actinomycetes and Their Secondary Metabolites |
| title_short | Deep Sea Actinomycetes and Their Secondary Metabolites |
| title_sort | deep sea actinomycetes and their secondary metabolites |
| topic | deep sea actinomycetes bioactive natural products biosynthesis novel species |
| url | http://journal.frontiersin.org/article/10.3389/fmicb.2017.00760/full |
| work_keys_str_mv | AT kuihong deepseaactinomycetesandtheirsecondarymetabolites AT manitakamjam deepseaactinomycetesandtheirsecondarymetabolites AT periyasamysivalingam deepseaactinomycetesandtheirsecondarymetabolites AT zinxindeng deepseaactinomycetesandtheirsecondarymetabolites |