Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges

Shayan Shirazian,1 Olufemi Aina,1 Youngjun Park,1 Nawsheen Chowdhury,1 Kathleen Leger,1 Linle Hou,1 Nobuyuki Miyawaki,1 Vandana S Mathur2 1Division of Nephrology, Department of Medicine, Winthrop University Hospital, Mineola, NY; 2Mathur Consulting, Woodside, CA, USA Abstract: Chronic kidney disease...

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Main Authors: Shirazian S, Aina O, Park Y, Chowdhury N, Leger K, Hou L, Miyawaki N, Mathur VS
Format: Article
Language:English
Published: Dove Medical Press 2017-01-01
Series:International Journal of Nephrology and Renovascular Disease
Subjects:
Online Access:https://www.dovepress.com/chronic-kidney-disease-associated-pruritus-impact-on-quality-of-life-a-peer-reviewed-article-IJNRD
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author Shirazian S
Aina O
Park Y
Chowdhury N
Leger K
Hou L
Miyawaki N
Mathur VS
author_facet Shirazian S
Aina O
Park Y
Chowdhury N
Leger K
Hou L
Miyawaki N
Mathur VS
author_sort Shirazian S
collection DOAJ
description Shayan Shirazian,1 Olufemi Aina,1 Youngjun Park,1 Nawsheen Chowdhury,1 Kathleen Leger,1 Linle Hou,1 Nobuyuki Miyawaki,1 Vandana S Mathur2 1Division of Nephrology, Department of Medicine, Winthrop University Hospital, Mineola, NY; 2Mathur Consulting, Woodside, CA, USA Abstract: Chronic kidney disease-associated pruritus (CKD-aP) is a distressing, often overlooked condition in patients with CKD and end-stage renal disease. It affects ~40% of patients with end-stage renal disease and has been associated with poor quality of life, poor sleep, depression, and mortality. Prevalence estimates vary based on the instruments used to diagnose CKD-aP, and standardized diagnostic instruments are sorely needed. Treatment studies have often yielded conflicting results. This is likely related to studies that are limited by small sample size, flawed designs, and nonstandardized diagnostic instruments. Several large well-designed treatment trials have recently been completed and may soon influence CKD-aP management. Keywords: pruritus, chronic kidney disease, uremia, end-stage renal disease, itching, depression
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spelling doaj.art-96f06bd4bf1c476e8693e80d76f9bd272022-12-22T01:23:22ZengDove Medical PressInternational Journal of Nephrology and Renovascular Disease1178-70582017-01-01Volume 10112630970Chronic kidney disease-associated pruritus: impact on quality of life and current management challengesShirazian SAina OPark YChowdhury NLeger KHou LMiyawaki NMathur VSShayan Shirazian,1 Olufemi Aina,1 Youngjun Park,1 Nawsheen Chowdhury,1 Kathleen Leger,1 Linle Hou,1 Nobuyuki Miyawaki,1 Vandana S Mathur2 1Division of Nephrology, Department of Medicine, Winthrop University Hospital, Mineola, NY; 2Mathur Consulting, Woodside, CA, USA Abstract: Chronic kidney disease-associated pruritus (CKD-aP) is a distressing, often overlooked condition in patients with CKD and end-stage renal disease. It affects ~40% of patients with end-stage renal disease and has been associated with poor quality of life, poor sleep, depression, and mortality. Prevalence estimates vary based on the instruments used to diagnose CKD-aP, and standardized diagnostic instruments are sorely needed. Treatment studies have often yielded conflicting results. This is likely related to studies that are limited by small sample size, flawed designs, and nonstandardized diagnostic instruments. Several large well-designed treatment trials have recently been completed and may soon influence CKD-aP management. Keywords: pruritus, chronic kidney disease, uremia, end-stage renal disease, itching, depressionhttps://www.dovepress.com/chronic-kidney-disease-associated-pruritus-impact-on-quality-of-life-a-peer-reviewed-article-IJNRDprurituschronic kidney diseaseuremiaend stage renal diseaseitchingdepression
spellingShingle Shirazian S
Aina O
Park Y
Chowdhury N
Leger K
Hou L
Miyawaki N
Mathur VS
Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges
International Journal of Nephrology and Renovascular Disease
pruritus
chronic kidney disease
uremia
end stage renal disease
itching
depression
title Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges
title_full Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges
title_fullStr Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges
title_full_unstemmed Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges
title_short Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges
title_sort chronic kidney disease associated pruritus impact on quality of life and current management challenges
topic pruritus
chronic kidney disease
uremia
end stage renal disease
itching
depression
url https://www.dovepress.com/chronic-kidney-disease-associated-pruritus-impact-on-quality-of-life-a-peer-reviewed-article-IJNRD
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