Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges
Shayan Shirazian,1 Olufemi Aina,1 Youngjun Park,1 Nawsheen Chowdhury,1 Kathleen Leger,1 Linle Hou,1 Nobuyuki Miyawaki,1 Vandana S Mathur2 1Division of Nephrology, Department of Medicine, Winthrop University Hospital, Mineola, NY; 2Mathur Consulting, Woodside, CA, USA Abstract: Chronic kidney disease...
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Format: | Article |
Language: | English |
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Dove Medical Press
2017-01-01
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Series: | International Journal of Nephrology and Renovascular Disease |
Subjects: | |
Online Access: | https://www.dovepress.com/chronic-kidney-disease-associated-pruritus-impact-on-quality-of-life-a-peer-reviewed-article-IJNRD |
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author | Shirazian S Aina O Park Y Chowdhury N Leger K Hou L Miyawaki N Mathur VS |
author_facet | Shirazian S Aina O Park Y Chowdhury N Leger K Hou L Miyawaki N Mathur VS |
author_sort | Shirazian S |
collection | DOAJ |
description | Shayan Shirazian,1 Olufemi Aina,1 Youngjun Park,1 Nawsheen Chowdhury,1 Kathleen Leger,1 Linle Hou,1 Nobuyuki Miyawaki,1 Vandana S Mathur2 1Division of Nephrology, Department of Medicine, Winthrop University Hospital, Mineola, NY; 2Mathur Consulting, Woodside, CA, USA Abstract: Chronic kidney disease-associated pruritus (CKD-aP) is a distressing, often overlooked condition in patients with CKD and end-stage renal disease. It affects ~40% of patients with end-stage renal disease and has been associated with poor quality of life, poor sleep, depression, and mortality. Prevalence estimates vary based on the instruments used to diagnose CKD-aP, and standardized diagnostic instruments are sorely needed. Treatment studies have often yielded conflicting results. This is likely related to studies that are limited by small sample size, flawed designs, and nonstandardized diagnostic instruments. Several large well-designed treatment trials have recently been completed and may soon influence CKD-aP management. Keywords: pruritus, chronic kidney disease, uremia, end-stage renal disease, itching, depression |
first_indexed | 2024-12-11T02:48:58Z |
format | Article |
id | doaj.art-96f06bd4bf1c476e8693e80d76f9bd27 |
institution | Directory Open Access Journal |
issn | 1178-7058 |
language | English |
last_indexed | 2024-12-11T02:48:58Z |
publishDate | 2017-01-01 |
publisher | Dove Medical Press |
record_format | Article |
series | International Journal of Nephrology and Renovascular Disease |
spelling | doaj.art-96f06bd4bf1c476e8693e80d76f9bd272022-12-22T01:23:22ZengDove Medical PressInternational Journal of Nephrology and Renovascular Disease1178-70582017-01-01Volume 10112630970Chronic kidney disease-associated pruritus: impact on quality of life and current management challengesShirazian SAina OPark YChowdhury NLeger KHou LMiyawaki NMathur VSShayan Shirazian,1 Olufemi Aina,1 Youngjun Park,1 Nawsheen Chowdhury,1 Kathleen Leger,1 Linle Hou,1 Nobuyuki Miyawaki,1 Vandana S Mathur2 1Division of Nephrology, Department of Medicine, Winthrop University Hospital, Mineola, NY; 2Mathur Consulting, Woodside, CA, USA Abstract: Chronic kidney disease-associated pruritus (CKD-aP) is a distressing, often overlooked condition in patients with CKD and end-stage renal disease. It affects ~40% of patients with end-stage renal disease and has been associated with poor quality of life, poor sleep, depression, and mortality. Prevalence estimates vary based on the instruments used to diagnose CKD-aP, and standardized diagnostic instruments are sorely needed. Treatment studies have often yielded conflicting results. This is likely related to studies that are limited by small sample size, flawed designs, and nonstandardized diagnostic instruments. Several large well-designed treatment trials have recently been completed and may soon influence CKD-aP management. Keywords: pruritus, chronic kidney disease, uremia, end-stage renal disease, itching, depressionhttps://www.dovepress.com/chronic-kidney-disease-associated-pruritus-impact-on-quality-of-life-a-peer-reviewed-article-IJNRDprurituschronic kidney diseaseuremiaend stage renal diseaseitchingdepression |
spellingShingle | Shirazian S Aina O Park Y Chowdhury N Leger K Hou L Miyawaki N Mathur VS Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges International Journal of Nephrology and Renovascular Disease pruritus chronic kidney disease uremia end stage renal disease itching depression |
title | Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges |
title_full | Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges |
title_fullStr | Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges |
title_full_unstemmed | Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges |
title_short | Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges |
title_sort | chronic kidney disease associated pruritus impact on quality of life and current management challenges |
topic | pruritus chronic kidney disease uremia end stage renal disease itching depression |
url | https://www.dovepress.com/chronic-kidney-disease-associated-pruritus-impact-on-quality-of-life-a-peer-reviewed-article-IJNRD |
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