HMGCR gene polymorphism is associated with residual cholesterol risk in premature triple-vessel disease patients treated with moderate-intensity statins

HMGCR gene polymorphism is associated with residual cholesterol risk in premature triple-vessel disease patients treated with moderate-intensity statins

Abstract Background To investigate the association of HMGCR and NPC1L1 gene polymorphisms with residual cholesterol risk (RCR) in patients with premature triple-vessel disease (PTVD). Methods Three SNPs within HMGCR including rs12916, rs2303151, and rs4629571, and four SNPs within NPC1L1 including r...

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Bibliographic Details
Main Authors: Jiawen Li, Xiaofang Tang, Jingjing Xu, Ru Liu, Lin Jiang, Lianjun Xu, Jian Tian, Xinxing Feng, Yajie Wu, Yin Zhang, Dong Wang, Kai Sun, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Lei Song, Jinqing Yuan, Xueyan Zhao
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Cardiovascular Disorders
Subjects:
Gene polymorphisms
Residual cholesterol risk
Low-density lipoprotein cholesterol
Premature triple-vessel disease
Online Access:https://doi.org/10.1186/s12872-023-03285-w

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