CD215+ Myeloid Cells Respond to Interleukin 15 Stimulation and Promote Tumor Progression

CD215+ Myeloid Cells Respond to Interleukin 15 Stimulation and Promote Tumor Progression

Interleukin 15 (IL-15) regulates the development, survival, and functions of multiple innate and adaptive immune cells and plays a dual role in promoting both tumor cell growth and antitumor immunity. Here, we demonstrated that the in vivo injection of recombinant human IL-15 (200 µg/kg) or murine I...

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Bibliographic Details
Main Authors: Shouheng Lin, Guohua Huang, Yiren Xiao, Wei Sun, Yuchuan Jiang, Qiuhua Deng, Muyun Peng, Xinru Wei, Wei Ye, Baiheng Li, Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Yangqiu Li, Xuchao Zhang, Yilong Wu, Pentao Liu, Duanqing Pei, Fenglei Yu, Zhesheng Wen, Yao Yao, Donghai Wu, Peng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
interleukin 15
CD215
IGF-1
patient-derived xenograft
lung cancer
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01713/full

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