MicroRNA signature and integrative omics analyses define prognostic clusters and key pathways driving prognosis in patients with neuroendocrine neoplasms

MicroRNA signature and integrative omics analyses define prognostic clusters and key pathways driving prognosis in patients with neuroendocrine neoplasms

Neuroendocrine neoplasms (NENs) are mutationally quiet (low number of mutations/Mb), and epigenetic mechanisms drive their development and progression. We aimed at comprehensively characterising the microRNA (miRNA) profile of NENs, and exploring downstream targets and their epigenetic modulation. I...

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Bibliographic Details
Main Authors: Beatriz Soldevilla, Alberto Lens‐Pardo, Paula Espinosa‐Olarte, Carlos Carretero‐Puche, Sonia Molina‐Pinelo, Carlos Robles, Marta Benavent, Lourdes Gomez‐Izquierdo, Marta Fierro‐Fernández, Patricia Morales‐Burgo, Paula Jimenez‐Fonseca, Beatriz Anton‐Pascual, Yolanda Rodriguez‐Gil, Ana Teijo‐Quintans, Anna La Salvia, Beatriz Rubio‐Cuesta, Maria C. Riesco‐Martínez, Rocio Garcia‐Carbonero
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Molecular Oncology
Subjects:
miRNAs
NEN biology
NEN patients
prognostic impact
Online Access:https://doi.org/10.1002/1878-0261.13393

Internet

https://doi.org/10.1002/1878-0261.13393

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