Effect of Intensity of Cigarette Smoking on Haematological and Lipid Parameters
Background: Smoking is the single largest preventable cause of disease and premature death and major tobacco related diseases like cancer costs India more than Rs.308.33 billion per year. Cigarette smoking increases the total peripheral blood leukocyte count but its effect on other haematologica...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/4612/9545_CE[Ra1]_F(DK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Background: Smoking is the single largest preventable cause of
disease and premature death and major tobacco related diseases
like cancer costs India more than Rs.308.33 billion per year.
Cigarette smoking increases the total peripheral blood leukocyte
count but its effect on other haematological parameters is largely
unexplored.
Objective: To study the effect of smoking and its intensity on
hematological and lipid parameters.
Materials and Methods: This cross sectional study included 40
cigarette smokers and 40 non-smokers in the age range of 25 and
40 years at SRM Medical College, Kattangulathur, Tamilnadu,
India. In this study the volunteers were otherwise healthy and the
smokers were enquired about their intensity of smoking using
smoking index. Common hematological and lipid parameters
were measured in all subjects. Comparison of smoking status
and its intensity among the study subjects were analysed using
t-test and ANOVA.
Results: There is a significant increase in levels of haemoglobin,
hematocrit, total leukocyte count, total cholesterol, triglycerides,
low density lipoprotein (LDL), very low density lipoprotein (VLDL)
and reduced levels of high density lipoprotein (HDL) among
the smokers. Heavy smokers showed significant dyslipidemia,
increase in red blood cell count, total leukocyte count and
neutrophil count.
Conclusion: Increase in hemoglobin, hematocrit, total leucocyte
count and dyslipidemia were found significant among smokers
and in heavy smokers there is dyslipidemia with increased RBC
count, total leukocyte count with specific increase in neutrophils.
As per the existing literature, these changes may lead to future
fatal cardiac diseases among the smokers. |
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| ISSN: | 2249-782X 0973-709X |