Super enhancers: Pathogenic roles and potential therapeutic targets for acute myeloid leukemia (AML)

Super enhancers: Pathogenic roles and potential therapeutic targets for acute myeloid leukemia (AML)

Acute myeloid leukemia (AML) is a malignant hematological tumor with disordered oncogenes/tumor suppressor genes and limited treatments. The potent anti-cancer effects of bromodomain and extra-terminal domain (BET) inhibitors, targeting the key component of super enhancers, in early clinical trials...

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Bibliographic Details
Main Authors: Ziyang Cao, Yi Shu, Jinxia Wang, Chunxia Wang, Tienan Feng, Li Yang, Jingbo Shao, Lin Zou
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-11-01
Series:Genes and Diseases
Subjects:
AML
Classification
Leukemogenesis
Super enhancer
Therapy targets
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222000484

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