Super enhancers: Pathogenic roles and potential therapeutic targets for acute myeloid leukemia (AML)

Super enhancers: Pathogenic roles and potential therapeutic targets for acute myeloid leukemia (AML)

Acute myeloid leukemia (AML) is a malignant hematological tumor with disordered oncogenes/tumor suppressor genes and limited treatments. The potent anti-cancer effects of bromodomain and extra-terminal domain (BET) inhibitors, targeting the key component of super enhancers, in early clinical trials...

Bibliografiset tiedot
Päätekijät:	Ziyang Cao, Yi Shu, Jinxia Wang, Chunxia Wang, Tienan Feng, Li Yang, Jingbo Shao, Lin Zou
Aineistotyyppi:	Artikkeli
Kieli:	English
Julkaistu:	KeAi Communications Co., Ltd. 2022-11-01
Sarja:	Genes and Diseases
Aiheet:	AML Classification Leukemogenesis Super enhancer Therapy targets
Linkit:	http://www.sciencedirect.com/science/article/pii/S2352304222000484

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