Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up
Background: Endometrial hyperplasia (EH) is considered a heterogeneous pre-neoplastic clinical entity characterized by an abnormal glandular proliferation, with less than half of the tissue area occupied by the stroma. The aim of this retrospective study was to evaluate the correlation between the h...
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| Format: | Article |
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IMR Press
2022-01-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
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| Online Access: | https://www.imrpress.com/journal/CEOG/49/1/10.31083/j.ceog4901024 |
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| author | Luigi Nappi Stefano Angioni Vincenzo De Feo Pantaleo Greco Guglielmo Stabile Francesca Greco Maurizio Nicola D'Alterio Felice Sorrentino |
| author_facet | Luigi Nappi Stefano Angioni Vincenzo De Feo Pantaleo Greco Guglielmo Stabile Francesca Greco Maurizio Nicola D'Alterio Felice Sorrentino |
| author_sort | Luigi Nappi |
| collection | DOAJ |
| description | Background: Endometrial hyperplasia (EH) is considered a heterogeneous pre-neoplastic clinical entity characterized by an abnormal glandular proliferation, with less than half of the tissue area occupied by the stroma. The aim of this retrospective study was to evaluate the correlation between the histological diagnosis of atypical endometrial hyperplasia (AEH) obtained through office hysteroscopy (OH) or uterine dilation and curettage (D&C) and the definitive histological evaluation after hysterectomy. Methods: Among 112 patients with atypical EH, 45 (40%) underwent hysteroscopy and 67 (60%) curettage. Results: The diagnostic accuracy of OH was very high: in particular, it showed a diagnostic coincidence in 87% of cases with the definitive histological diagnosis through hysteroscopy. The curettage, instead, had diagnostic coincidence only in 14% of cases. Conclusion: Office hysteroscopy is the ideal procedure for both diagnosis and follow-up of endometrial hyperplasia. |
| first_indexed | 2024-04-14T04:53:12Z |
| format | Article |
| id | doaj.art-96fbc2fa029e44128478ff95a06aebf2 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-04-14T04:53:12Z |
| publishDate | 2022-01-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-96fbc2fa029e44128478ff95a06aebf22022-12-22T02:11:14ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632022-01-014912410.31083/j.ceog4901024S0390-6663(22)01673-6Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-upLuigi Nappi0Stefano Angioni1Vincenzo De Feo2Pantaleo Greco3Guglielmo Stabile4Francesca Greco5Maurizio Nicola D'Alterio6Felice Sorrentino7Department of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, ItalyDepartment of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, 09124 Cagliari, ItalyDepartment of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, ItalyDepartment of Medical Sciences, Section of Obstetric and Gynaecology, University of Ferrara, 44121 Ferrara, ItalyDepartment of Obstetrics and Gynecology, Institute for Maternal and Child Health IRCCS ``Burlo Garofolo'', 34137 Trieste, ItalyDepartment of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, ItalyDepartment of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, 09124 Cagliari, ItalyDepartment of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, ItalyBackground: Endometrial hyperplasia (EH) is considered a heterogeneous pre-neoplastic clinical entity characterized by an abnormal glandular proliferation, with less than half of the tissue area occupied by the stroma. The aim of this retrospective study was to evaluate the correlation between the histological diagnosis of atypical endometrial hyperplasia (AEH) obtained through office hysteroscopy (OH) or uterine dilation and curettage (D&C) and the definitive histological evaluation after hysterectomy. Methods: Among 112 patients with atypical EH, 45 (40%) underwent hysteroscopy and 67 (60%) curettage. Results: The diagnostic accuracy of OH was very high: in particular, it showed a diagnostic coincidence in 87% of cases with the definitive histological diagnosis through hysteroscopy. The curettage, instead, had diagnostic coincidence only in 14% of cases. Conclusion: Office hysteroscopy is the ideal procedure for both diagnosis and follow-up of endometrial hyperplasia.https://www.imrpress.com/journal/CEOG/49/1/10.31083/j.ceog4901024endometrial hyperplasia (eh)office hysteroscopy (oh)dilation and curettage (d&c)transvaginal ultrasound (tvus)endometrial biopsy (eb)endometrial carcinoma |
| spellingShingle | Luigi Nappi Stefano Angioni Vincenzo De Feo Pantaleo Greco Guglielmo Stabile Francesca Greco Maurizio Nicola D'Alterio Felice Sorrentino Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up Clinical and Experimental Obstetrics & Gynecology endometrial hyperplasia (eh) office hysteroscopy (oh) dilation and curettage (d&c) transvaginal ultrasound (tvus) endometrial biopsy (eb) endometrial carcinoma |
| title | Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up |
| title_full | Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up |
| title_fullStr | Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up |
| title_full_unstemmed | Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up |
| title_short | Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up |
| title_sort | diagnostic accuracy of hysteroscopy vs dilation and curettage d c for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow up |
| topic | endometrial hyperplasia (eh) office hysteroscopy (oh) dilation and curettage (d&c) transvaginal ultrasound (tvus) endometrial biopsy (eb) endometrial carcinoma |
| url | https://www.imrpress.com/journal/CEOG/49/1/10.31083/j.ceog4901024 |
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