New insights into the roles of the FOXO3 and P27Kip1 genes in signaling pathways

New insights into the roles of the FOXO3 and P27Kip1 genes in signaling pathways

Background: The forkhead box O3 (FOXO3) and p27Kip1 are two important genes in breast cancer progression. In the present study we analyzed the effect of simultaneous FOXO3 silencing and p27Kip1 activation on breast cancer cell survival and the potential targets of these changes in cancer molecular p...

Full description

Bibliographic Details
Main Authors:	Sabah Mayahi, Masood Golalipour, Ahad Yamchi, Gagan Deep Jhingan, Majid Shahbazi
Format:	Article
Language:	English
Published:	Upsala Medical Society 2019-07-01
Series:	Upsala Journal of Medical Sciences
Subjects:	breast cancer cell signaling foxo3a gene therapy p27kip1 proteomics
Online Access:	http://dx.doi.org/10.1080/03009734.2019.1623351

Similar Items

Regulation of p27<sup>Kip1</sup> and p57<sup>Kip2</sup> Functions by Natural Polyphenols
by: Gian Luigi Russo, et al.
Published: (2020-09-01)

p27KIP1 Deletions in Childhood Acute Lymphoblastic Leukemia
by: Hiroaki Komuro, et al.
Published: (1999-08-01)

p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway
by: Pauline Jeannot, et al.
Published: (2017-03-01)

Loss of p27Kip1 expression in high grade human prostate adenocarcinoma
by: MOHD ROHAIZAD MD. RODUAN, et al.
Published: (2014-08-01)

p27<sup>kip1</sup> Modulates the Morphology and Phagocytic Activity of Microglia
by: Jolien Beeken, et al.
Published: (2022-09-01)

Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway
by: Yang Song, et al.
Published: (2015-01-01)

Identification of hub genes associated with RNAi-induced silencing of XIAP through targeted proteomics approach in MCF7 cells
by: Mehdi Agha Gholizadeh, et al.
Published: (2020-06-01)

p27<sup>Kip1</sup>, an Intrinsically Unstructured Protein with Scaffold Properties
by: Debora Bencivenga, et al.
Published: (2021-08-01)

miR-155 effectively induces apoptosis in K562 Philadelphia positive cell line through upregulation of p27kip1
by: Mahdi Edalati Fathabad, et al.
Published: (2017-06-01)

Data Mining for Identification of Forkhead Box O (FOXO3a) in Different Organisms Using Nucleotide and Tandem Repeat Sequences
by: Sabah Mayahi, et al.
Published: (2020-02-01)

A single-nucleotide polymorphism in the human p27<sup>kip1 </sup>gene (-838C>A) affects basal promoter activity and the risk of myocardial infarction
by: Reguero Julian R, et al.
Published: (2004-04-01)

Cell type-specific effects of p27KIP1 loss on retinal development
by: Mariko Ogawa, et al.
Published: (2017-09-01)

Dysregulation of the Mammalian Target of Rapamycin and p27Kip1 Promotes Intimal Hyperplasia in Diabetes Mellitus
by: Thomas Cooper Woods
Published: (2013-05-01)

Perbedaan Orientasi Masa Depan Mahasiswa Tingkat Akhir Penerima KIP-K dan Non KIP-K di Program Studi Psikologi Universitas Malikussaleh
by: Ika Amalia, et al.
Published: (2023-12-01)

Temel Tümcelerde ve Ortaçlı Yapılarda Kip Anlatımı
by: Şeyda Özil
Published: (1994-02-01)

Alterations in TP53, cyclin D2, c-Myc, p21WAF1/CIP1 and p27KIP1 expression associated with progression in B-CLL
by: Antosz Halina, et al.
Published: (2010-04-01)

Decision-Making System for KIP IAIN Bukittinggi Scholarship Recipients Using the SAW and TOPSIS Methods
by: Uqwatul Alma Wizsa, et al.
Published: (2022-06-01)

Increased Expression of NPM1 Suppresses p27<sup>Kip1</sup> Function in Cancer Cells
by: Tatsuya Kometani, et al.
Published: (2020-10-01)

Performance Improvement of K-Nearest Neighbor Algorithm in KIP Scholarship Recipient Selection
by: Manzilur Rahman Romadhon, et al.
Published: (2023-10-01)

ANO1 Expression Orchestrates p27Kip1/MCL1-Mediated Signaling in Head and Neck Squamous Cell Carcinoma
by: Artemis Filippou, et al.
Published: (2021-03-01)

Loss of p27Kip1 leads to expansion of CD4+ effector memory T cells and accelerates colitis-associated colon cancer in mice with a T cell lineage restricted deletion of Smad4
by: Sung Hee Choi, et al.
Published: (2020-01-01)

Hubungan persepsi siswa tentang KIP kuliah dengan keputusan melanjutkan pendidikan ke perguruan tinggi
by: Dian Montanesa, et al.
Published: (2023-06-01)

Combination of Profile Matching and SAW Methods for College KIP Admission
by: Riya Majalista, et al.
Published: (2023-09-01)

Role of P27kip1 Protein, P45skp2 Coactivator, and P38jab1 Coactivator in Preventing Rhabdomyosarcoma (RMS) in Oral Cavity of Children
by: Inne Suherna Sasmita, et al.
Published: (2022-06-01)

بررسی فراوانی بیان پروتئین P27 درکارسینوم سلول سنگفرشی دهان و مری
by: فاطمه شاهسواری, et al.
Published: (2012-09-01)

Electro-gene therapy followed by intratumoral injection of pcDNA3.1-p27Kip1 wild type in human tongue base cancer cells SP-C3 xenograft
by: S. Supriatno, et al.
Published: (2009-11-01)

P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus
by: Woosuk Kim, et al.
Published: (2020-12-01)

Content Validity of KIP-K Scholarship Instruments at Higher Education Using Aiken's Coefficient Validity Scale
by: Sabaruddin Sabaruddin, et al.
Published: (2022-07-01)

p27, The Cell Cycle and Alzheimer´s Disease
by: Ana García-Osta, et al.
Published: (2022-01-01)

Tissue-Specific Metabolic Regulation of FOXO-Binding Protein: FOXO Does Not Act Alone
by: Noriko Kodani, et al.
Published: (2020-03-01)

The Learning Patterns of Self Regulated Learning in Increasing Achievement of Recipient Students KIP Scholarship Period 2020/2021 PAI Program Faculty of Tarbiyah IAIN Bone
by: Hasbi Siddik, et al.
Published: (2023-08-01)

Functional Versatility of the CDK Inhibitor p57Kip2
by: Justine Creff, et al.
Published: (2020-10-01)

CIP/KIP and INK4 families as hostages of oncogenic signaling
by: Lucia Csergeová, et al.
Published: (2024-04-01)

Formononetin Inhibits Progression of Endometriosis via Regulation of p27, pSTAT3, and Progesterone Receptor: In Vitro and In Vivo Studies
by: Yunjeong Park, et al.
Published: (2023-06-01)

Partial hepatectomy in rats results in immediate down-regulation of p27Kip1 in residual liver tissue by transcriptional and post-translational processes
by: Anne-Katrin eRohlfing, et al.
Published: (2013-06-01)

Determination of morphologic and immunohistochemical stain (p57 kip2) discrepancy of complete and partial hydatidiform mole by using microsatellite genotyping
by: Shina Oranratanaphan, et al.
Published: (2020-07-01)

ATG7 Overexpression Is Crucial for Tumorigenic Growth of Bladder Cancer In Vitro and In Vivo by Targeting the ETS2/miRNA196b/FOXO1/p27 Axis
by: Junlan Zhu, et al.
Published: (2017-06-01)

Azaltan DA-DA Dönüştürücüsü İçin Kayma Kip Denetleyici Tasarımı
by: Fatih Evran
Published: (2019-01-01)

FOXO1 Regulates Bacteria-Induced Neutrophil Activity
by: Guangyu Dong, et al.
Published: (2017-09-01)

Role and regulation of FOXO3a: new insights into breast cancer therapy
by: Wenqiu Mei, et al.
Published: (2024-03-01)