Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi

Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi

Summary: Neutrophil swarming is an emergent host defense mechanism triggered by targets larger than a single neutrophil’s capacity to phagocytose. Swarming synergizes neutrophil functions, including chemotaxis, phagocytosis, and reactive oxygen species (ROS) production, and coordinates their deploym...

Full description

Bibliographic Details
Main Authors:	Alex Hopke, Tian Lin, Allison K. Scherer, Ashley E. Shay, Kyle D. Timmer, Brittany Wilson-Mifsud, Michael K. Mansour, Charles N. Serhan, Daniel Irimia, Bryan P. Hurley
Format:	Article
Language:	English
Published:	Elsevier 2022-10-01
Series:	iScience
Subjects:	Immunology Cell biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004222014985

Similar Items

Biosynthesis of eicosanoids and transcellular metabolism of leukotrienes in murine bone marrow cells
by: Miguel A. Gijón, et al.
Published: (2007-03-01)

Neutrophil swarming delays the growth of clusters of pathogenic fungi
by: Alex Hopke, et al.
Published: (2020-04-01)

Publisher Correction: Neutrophil swarming delays the growth of clusters of pathogenic fungi
by: Alex Hopke, et al.
Published: (2020-05-01)

Chemotaxis and swarming in differentiated HL-60 neutrophil-like cells
by: Kehinde Adebayo Babatunde, et al.
Published: (2021-01-01)

Redox processes are major regulators of leukotriene synthesis in neutrophils exposed to bacteria Salmonella typhimurium; the way to manipulate neutrophil swarming
by: Ekaterina A. Golenkina, et al.
Published: (2024-02-01)

Vascular transcellular signaling.
by: Aaron J. Marcus, et al.
Published: (1993-12-01)

Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids /
by: Fumiyuki Kiuchi

Endothelial domes encapsulate adherent neutrophils and minimize increases in vascular permeability in paracellular and transcellular emigration.
by: Mia Phillipson, et al.
Published: (2008-01-01)

Gram-Negative Bacteria Salmonella typhimurium Boost Leukotriene Synthesis Induced by Chemoattractant fMLP to Stimulate Neutrophil Swarming
by: Ekaterina A. Golenkina, et al.
Published: (2022-01-01)

Transcellular migration of neutrophil granulocytes through the blood-cerebrospinal fluid barrier after infection with <it>Streptococcus suis</it>
by: Quitsch Ulrike, et al.
Published: (2011-05-01)

The Transcellular Propagation and Intracellular Trafficking of α-Synuclein
by: Tofaris, GK, et al.
Published: (2016)

The direct transfer approach for transcellular drug delivery
by: Yi-Fan Wang, et al.
Published: (2023-12-01)

Current Update on Transcellular Brain Drug Delivery
by: Bhakti Pawar, et al.
Published: (2022-12-01)

Neutrophils: Orchestrators of the Malignant Phenotype
by: Brian E. Hsu, et al.
Published: (2020-08-01)

Neutrophils Orchestrate the Periodontal Pocket
by: Ljubomir Vitkov, et al.
Published: (2021-11-01)

Loss of Coordinated Neutrophil Responses to the Human Fungal Pathogen, Candida albicans, in Patients With Cirrhosis
by: Sally A.I. Knooihuizen, et al.
Published: (2021-03-01)

The BLT1 inhibitory function of α-1 antitrypsin augmentation therapy disrupts leukotriene B4 neutrophil signaling
by: O’Dwyer, C, et al.
Published: (2015)

An on-chip model of protein paracellular and transcellular permeability in the microcirculation
by: Offeddu, Giovanni, et al.
Published: (2020)

A novel type of <it>Plasmodium</it> sporozoite transcellular migration
by: Amino Rogerio, et al.
Published: (2010-10-01)

Editorial "Transcellular Cycles underlying Neurotransmission"
by: Sebastian eCerdan, et al.
Published: (2015-06-01)

Biosynthesis of a linoleic acid allylic epoxide: mechanistic comparison with its chemical synthesis and leukotriene A biosynthesis[S]
by: Katrin Niisuke, et al.
Published: (2009-07-01)

Paracellular and Transcellular Leukocytes Diapedesis Are Divergent but Interconnected Evolutionary Events
by: Michel-Edwar Mickael, et al.
Published: (2021-02-01)

Multiparametric Profiling of Neutrophil Function via a High-Throughput Flow Cytometry-Based Assay
by: Kyle D. Timmer, et al.
Published: (2023-02-01)

The IRE1α Inhibitor KIRA6 Blocks Leukotriene Biosynthesis in Human Phagocytes
by: Xiao Tang, et al.
Published: (2022-03-01)

Leukotriene biosynthesis inhibition ameliorates acute lung injury following hemorrhagic shock in rats
by: Hadi Najah R, et al.
Published: (2011-06-01)

Mitochondria-targeted antioxidant SkQ1 inhibits leukotriene synthesis in human neutrophils
by: Galina F. Sud’ina, et al.
Published: (2022-11-01)

Differential impact of 5-lipoxygenase-activating protein antagonists on the biosynthesis of leukotrienes and of specialized pro-resolving mediators
by: Philipp Dahlke, et al.
Published: (2023-08-01)

Transcellular passage of Neisseria meningitidis across a polarized respiratory epithelium.
by: Sutherland, T, et al.
Published: (2010)

Activation of NMDA receptors in brain endothelial cells increases transcellular permeability
by: Kyu-Sung Kim, et al.
Published: (2022-09-01)

Transplacental transfer mechanism of organochlorine pesticides: An in vitro transcellular transport study
by: Shanshan Yin, et al.
Published: (2020-02-01)

Ovarian endometrioma infiltrating neutrophils orchestrate immunosuppressive microenvironment
by: Hua Xu, et al.
Published: (2020-04-01)

The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses.
by: Angela B Schmider, et al.
Published: (2019-01-01)

Substituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition, and Cytotoxic Activity
by: Pier Morin, et al.
Published: (2017-07-01)

Magic Peptide: Unique Properties of the LRR11 Peptide in the Activation of Leukotriene Synthesis in Human Neutrophils
by: Galina M. Viryasova, et al.
Published: (2021-03-01)

Hypercholesterolemia Increases the Production of Leukotriene B4 in Neutrophils by Enhancing the Nuclear Localization of 5-Lipoxygenase
by: Xiao-Feng Lai, et al.
Published: (2014-11-01)

Leukotrienes Are Dispensable for Vaginal Neutrophil Recruitment as Part of the Immunopathological Response During Experimental Vulvovaginal Candidiasis
by: Junko Yano, et al.
Published: (2021-11-01)

Enabling Wireless-Powered IoT Through Incentive-Based UAV Swarm Orchestration
by: Prodromos-Vasileios Mekikis, et al.
Published: (2023-01-01)

The iron chelator, PBT434, modulates transcellular iron trafficking in brain microvascular endothelial cells.
by: Danielle K Bailey, et al.
Published: (2021-01-01)

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation
by: Patrick Reilly, et al.
Published: (2017-10-01)

Quantifying the relative importance of transcellular and paracellular ion transports to coral polyp calcification
by: Sönke eHohn, et al.
Published: (2015-01-01)