RAT DENTAL PULP RESPONSE TO PROPOLIS AS A DIRECT PULP CAPPING AGENT

The aim of the present study was to assess the response of rat dental pulp to direct pulp capping with ethanol extracts of propolis (EEP). An occlusal cavity was prepared on the right maxillary first molar of Spraque-Dawley rats. The dental pulp was exposed and the lined with a zinc-oxide based fill...

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Main Author: Sabir Ardo
Format: Article
Language:English
Published: Faculty of Dentistry, Universitas Indonesia 2006-04-01
Series:Journal of Dentistry Indonesia
Subjects:
Online Access:http://jdentistry.ui.ac.id/index.php/JDI/article/view/277
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author Sabir Ardo
author_facet Sabir Ardo
author_sort Sabir Ardo
collection DOAJ
description The aim of the present study was to assess the response of rat dental pulp to direct pulp capping with ethanol extracts of propolis (EEP). An occlusal cavity was prepared on the right maxillary first molar of Spraque-Dawley rats. The dental pulp was exposed and the lined with a zinc-oxide based filler as a control (group I), or with EEP (group II). Then, each cavity was filled with glass ionomer cement. The animals were sacrificed at week 1, 2, or 4. Biopsy samples were obtained, and these were stained and viewed by a light microscope. The histological examination was based on the presence of polymorph nuclear leukocytes and macrophages, and also the dentinal bridge formation. Data were statistically analysed using Kruskall-Wallis and Mann-Whitney tests. The results showed that the inflammatory response of EEP group was relatively milder compared to the control group, but there was no significant difference (p>0.05) between the two groups. There was no dentinal bridge formation seen in both groups. Therefore, the present results suggest that direct pulp capping with EEP in rats may delay pulp inflammatory process and fail to stimulate reparative dentin.
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spelling doaj.art-9704096eccca4d38a7b5c4d2caffde5e2022-12-22T02:10:52ZengFaculty of Dentistry, Universitas IndonesiaJournal of Dentistry Indonesia1693-96972355-48002006-04-01131576110.14693/jdi.v13i1.277194RAT DENTAL PULP RESPONSE TO PROPOLIS AS A DIRECT PULP CAPPING AGENTSabir Ardo0Department of Conservative Dentistry, Faculty of Dentistry, Hasanudin UniversityThe aim of the present study was to assess the response of rat dental pulp to direct pulp capping with ethanol extracts of propolis (EEP). An occlusal cavity was prepared on the right maxillary first molar of Spraque-Dawley rats. The dental pulp was exposed and the lined with a zinc-oxide based filler as a control (group I), or with EEP (group II). Then, each cavity was filled with glass ionomer cement. The animals were sacrificed at week 1, 2, or 4. Biopsy samples were obtained, and these were stained and viewed by a light microscope. The histological examination was based on the presence of polymorph nuclear leukocytes and macrophages, and also the dentinal bridge formation. Data were statistically analysed using Kruskall-Wallis and Mann-Whitney tests. The results showed that the inflammatory response of EEP group was relatively milder compared to the control group, but there was no significant difference (p>0.05) between the two groups. There was no dentinal bridge formation seen in both groups. Therefore, the present results suggest that direct pulp capping with EEP in rats may delay pulp inflammatory process and fail to stimulate reparative dentin.http://jdentistry.ui.ac.id/index.php/JDI/article/view/277propolisdirect pulp cappinginflammatory responsedentinal bridge formationrat
spellingShingle Sabir Ardo
RAT DENTAL PULP RESPONSE TO PROPOLIS AS A DIRECT PULP CAPPING AGENT
Journal of Dentistry Indonesia
propolis
direct pulp capping
inflammatory response
dentinal bridge formation
rat
title RAT DENTAL PULP RESPONSE TO PROPOLIS AS A DIRECT PULP CAPPING AGENT
title_full RAT DENTAL PULP RESPONSE TO PROPOLIS AS A DIRECT PULP CAPPING AGENT
title_fullStr RAT DENTAL PULP RESPONSE TO PROPOLIS AS A DIRECT PULP CAPPING AGENT
title_full_unstemmed RAT DENTAL PULP RESPONSE TO PROPOLIS AS A DIRECT PULP CAPPING AGENT
title_short RAT DENTAL PULP RESPONSE TO PROPOLIS AS A DIRECT PULP CAPPING AGENT
title_sort rat dental pulp response to propolis as a direct pulp capping agent
topic propolis
direct pulp capping
inflammatory response
dentinal bridge formation
rat
url http://jdentistry.ui.ac.id/index.php/JDI/article/view/277
work_keys_str_mv AT sabirardo ratdentalpulpresponsetopropolisasadirectpulpcappingagent