Dose perturbation study in a multichannel breast brachytherapy device
Purpose: A study was conducted to determine the dosimetric effects resulting from air pockets and high atomic number(Z) contrast medium within a multichannel breast brachytherapy device. Material and methods: A 5-6 cm diameter Contura (SenoRx) brachytherapy device was inflated using 37 cm3 of saline...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2011-12-01
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| Series: | Journal of Contemporary Brachytherapy |
| Subjects: | |
| Online Access: | http://www.termedia.pl/Dose-perturbation-study-in-a-multichannel-breast-brachytherapy-device,54,17927,1,1.html |
| _version_ | 1818023960609030144 |
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| author | Indra J. Das Rodney Fletcher Eric D. Slessinger |
| author_facet | Indra J. Das Rodney Fletcher Eric D. Slessinger |
| author_sort | Indra J. Das |
| collection | DOAJ |
| description | Purpose: A study was conducted to determine the dosimetric effects resulting from air pockets and high atomic number(Z) contrast medium within a multichannel breast brachytherapy device. Material and methods: A 5-6 cm diameter Contura (SenoRx) brachytherapy device was inflated using 37 cm3 of saline.Baseline dose falloff from an HDR Iridium-192 source was measured with the Iridium source centered in the central channeland an anterior off-center channel. Data were collected at distances from 1 to 50mm. Comparison studies were conductedwith identically inflated volume containing varied air pocket volumes (1-4 cm3) and concentrations of contrastsolution (3%, 6%, and 9% by volume). Dose perturbation factors (DPF) were computed and evaluated. Results: Dose perturbations due to air pockets and contrast solutions were observed. As the volume of air increased,the DPF increased by approximately 2.25%/cm3. The effect was consistent for both channels. The contrast effects weremore complex. The 3% contrast media had minimal dose perturbation. The 6% contrast solution caused dose reductionof 1.0% from the central channel but 1.5% dose increase from the anterior channel. The 9% contrast solution caused dosereductions by 4.0% (from central channel) and 3.0% (from anterior channel). The DPF from all contrast solutions mode -rated with increasing distance. Conclusions: Dose perturbations due to air pockets and high-Z contrast solution can be significant. It is importantto control these effects to avoid dose errors. |
| first_indexed | 2024-12-10T03:52:37Z |
| format | Article |
| id | doaj.art-970543607b794d11992c97a30e2f5869 |
| institution | Directory Open Access Journal |
| issn | 1689-832X 2081-2841 |
| language | English |
| last_indexed | 2024-12-10T03:52:37Z |
| publishDate | 2011-12-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Journal of Contemporary Brachytherapy |
| spelling | doaj.art-970543607b794d11992c97a30e2f58692022-12-22T02:03:12ZengTermedia Publishing HouseJournal of Contemporary Brachytherapy1689-832X2081-28412011-12-0134220223Dose perturbation study in a multichannel breast brachytherapy deviceIndra J. DasRodney FletcherEric D. SlessingerPurpose: A study was conducted to determine the dosimetric effects resulting from air pockets and high atomic number(Z) contrast medium within a multichannel breast brachytherapy device. Material and methods: A 5-6 cm diameter Contura (SenoRx) brachytherapy device was inflated using 37 cm3 of saline.Baseline dose falloff from an HDR Iridium-192 source was measured with the Iridium source centered in the central channeland an anterior off-center channel. Data were collected at distances from 1 to 50mm. Comparison studies were conductedwith identically inflated volume containing varied air pocket volumes (1-4 cm3) and concentrations of contrastsolution (3%, 6%, and 9% by volume). Dose perturbation factors (DPF) were computed and evaluated. Results: Dose perturbations due to air pockets and contrast solutions were observed. As the volume of air increased,the DPF increased by approximately 2.25%/cm3. The effect was consistent for both channels. The contrast effects weremore complex. The 3% contrast media had minimal dose perturbation. The 6% contrast solution caused dose reductionof 1.0% from the central channel but 1.5% dose increase from the anterior channel. The 9% contrast solution caused dosereductions by 4.0% (from central channel) and 3.0% (from anterior channel). The DPF from all contrast solutions mode -rated with increasing distance. Conclusions: Dose perturbations due to air pockets and high-Z contrast solution can be significant. It is importantto control these effects to avoid dose errors.http://www.termedia.pl/Dose-perturbation-study-in-a-multichannel-breast-brachytherapy-device,54,17927,1,1.htmlbrachytherapybreast cancerdose perturbationPBI |
| spellingShingle | Indra J. Das Rodney Fletcher Eric D. Slessinger Dose perturbation study in a multichannel breast brachytherapy device Journal of Contemporary Brachytherapy brachytherapy breast cancer dose perturbation PBI |
| title | Dose perturbation study in a multichannel breast brachytherapy device |
| title_full | Dose perturbation study in a multichannel breast brachytherapy device |
| title_fullStr | Dose perturbation study in a multichannel breast brachytherapy device |
| title_full_unstemmed | Dose perturbation study in a multichannel breast brachytherapy device |
| title_short | Dose perturbation study in a multichannel breast brachytherapy device |
| title_sort | dose perturbation study in a multichannel breast brachytherapy device |
| topic | brachytherapy breast cancer dose perturbation PBI |
| url | http://www.termedia.pl/Dose-perturbation-study-in-a-multichannel-breast-brachytherapy-device,54,17927,1,1.html |
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