GMSC-Derived Exosomes Combined with a Chitosan/Silk Hydrogel Sponge Accelerates Wound Healing in a Diabetic Rat Skin Defect Model

GMSC-Derived Exosomes Combined with a Chitosan/Silk Hydrogel Sponge Accelerates Wound Healing in a Diabetic Rat Skin Defect Model

Background: Delayed wound healing in diabetic patients is one of the most challenging complications in clinical medicine, as it poses a greater risk of gangrene, amputation and even death. Therefore, a novel method to promote diabetic wound healing is of considerable interest at present. Previous st...

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Bibliographic Details
Main Authors: Quan Shi, Zhiyong Qian, Donghua Liu, Jie Sun, Xing Wang, Hongchen Liu, Juan Xu, Ximin Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Physiology
Subjects:
gingival mesenchymal stem cells
exosomes
hydrogel sponge
diabetic rats
skin repair and regeneration
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00904/full

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