hsdSA regulated extracellular vesicle-associated PLY to protect Streptococcus pneumoniae from macrophage killing via LAPosomes

hsdSA regulated extracellular vesicle-associated PLY to protect Streptococcus pneumoniae from macrophage killing via LAPosomes

ABSTRACT Streptococcus pneumoniae is a notorious human opportunistic pathogen which undergoes a spontaneous and reversible phenotypic change in response to the host environment. We demonstrated that the regulatory gene hsdSA of DNA methylation in the type I restriction modification system altered co...

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Bibliographic Details
Main Authors: Liping Wang, Mengyuan Liu, Yixin Qi, Jian Wang, Qixue Shi, Xiaolin Xie, Changlin Zhou, Lingman Ma
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
hsdSA
extracellular vesicles
PLY
Streptococcus pneumoniae
LAPosomes
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00995-23

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