Oxidative stress response as biomarker of exposure of a freshwater invertebrate model organism (Unio mancus Lamarck, 1819) to antifouling copper pyrithione
Sublethal effects of copper pyrithione (CuPT) on an invertebrate model organism, freshwater mussel (Unio mancus), were assessed using oxidative stress parameters and histopathology. The environmentally relevant concentration of 5 mg/l copper pyrithione was applied as a 96 h semi-static exposure. MDA...
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| Format: | Article |
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Institute of Pesticides and Environmental Protection
2022-01-01
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| Series: | Pesticidi i Fitomedicina |
| Subjects: | |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1820-3949/2022/1820-39492202063P.pdf |
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| author | Paçal Elif Gümüş Burçin Aşkım Günal Çağlan A. Erkmen Belda Arslan Pınar Yıldırım Zuhal Erkoç Figen |
| author_facet | Paçal Elif Gümüş Burçin Aşkım Günal Çağlan A. Erkmen Belda Arslan Pınar Yıldırım Zuhal Erkoç Figen |
| author_sort | Paçal Elif |
| collection | DOAJ |
| description | Sublethal effects of copper pyrithione (CuPT) on an invertebrate model organism, freshwater mussel (Unio mancus), were assessed using oxidative stress parameters and histopathology. The environmentally relevant concentration of 5 mg/l copper pyrithione was applied as a 96 h semi-static exposure. MDA levels in digestive gland (DG) significantly increased, compared to a control group (p < 0.001). Gill MDA levels also increased, but not significantly (p > 0.05). GSH level in DG increased significantly (p < 0.05), and gill tissue levels also increased but not significantly (p > 0.05). Levels of SOD, GPx activities, and AOPP levels did not change significantly (p > 0.05). The most prominent histopathological alterations in the gills were haemocyte infiltration, lipofuscin aggregates and lamellar deformations with tubule degeneration and accumulated lipofuscin aggregates in DG tubules. CuPT impacts antioxidant defense systems even during sublethal exposure of Unio mancus as the freshwater model organism. |
| first_indexed | 2024-04-11T19:04:18Z |
| format | Article |
| id | doaj.art-9717abc67f314b99a6f0b1ef238072ad |
| institution | Directory Open Access Journal |
| issn | 1820-3949 2406-1026 |
| language | English |
| last_indexed | 2024-04-11T19:04:18Z |
| publishDate | 2022-01-01 |
| publisher | Institute of Pesticides and Environmental Protection |
| record_format | Article |
| series | Pesticidi i Fitomedicina |
| spelling | doaj.art-9717abc67f314b99a6f0b1ef238072ad2022-12-22T04:07:50ZengInstitute of Pesticides and Environmental ProtectionPesticidi i Fitomedicina1820-39492406-10262022-01-01372637610.2298/PIF2202063P1820-39492202063POxidative stress response as biomarker of exposure of a freshwater invertebrate model organism (Unio mancus Lamarck, 1819) to antifouling copper pyrithionePaçal Elif0Gümüş Burçin Aşkım1Günal Çağlan A.2Erkmen Belda3Arslan Pınar4Yıldırım Zuhal5Erkoç Figen6Çankırı Karatekin University, Eldivan Vocational School of Health Services, Çankırı, TurkeyGazi University, Faculty of Science, Department of Biology, Ankara, TurkeyGazi University, Education Faculty, Department of Biology Education, Ankara, TurkeyAksaray University, Science and Letters Faculty, Department of Biology, Aksaray, TurkeyÇankırı Karatekin University, Faculty of Science, Department of Biology, Çankırı, TurkeyEtimesgut Public Health Laboratory, Etimesgut, Ankara, TurkeyGazi University, Education Faculty, Department of Biology Education, Ankara, TurkeySublethal effects of copper pyrithione (CuPT) on an invertebrate model organism, freshwater mussel (Unio mancus), were assessed using oxidative stress parameters and histopathology. The environmentally relevant concentration of 5 mg/l copper pyrithione was applied as a 96 h semi-static exposure. MDA levels in digestive gland (DG) significantly increased, compared to a control group (p < 0.001). Gill MDA levels also increased, but not significantly (p > 0.05). GSH level in DG increased significantly (p < 0.05), and gill tissue levels also increased but not significantly (p > 0.05). Levels of SOD, GPx activities, and AOPP levels did not change significantly (p > 0.05). The most prominent histopathological alterations in the gills were haemocyte infiltration, lipofuscin aggregates and lamellar deformations with tubule degeneration and accumulated lipofuscin aggregates in DG tubules. CuPT impacts antioxidant defense systems even during sublethal exposure of Unio mancus as the freshwater model organism.https://scindeks-clanci.ceon.rs/data/pdf/1820-3949/2022/1820-39492202063P.pdfbiocidesantifouling copper pyrithionebiomarkersoxidative stressfreshwater mussel |
| spellingShingle | Paçal Elif Gümüş Burçin Aşkım Günal Çağlan A. Erkmen Belda Arslan Pınar Yıldırım Zuhal Erkoç Figen Oxidative stress response as biomarker of exposure of a freshwater invertebrate model organism (Unio mancus Lamarck, 1819) to antifouling copper pyrithione Pesticidi i Fitomedicina biocides antifouling copper pyrithione biomarkers oxidative stress freshwater mussel |
| title | Oxidative stress response as biomarker of exposure of a freshwater invertebrate model organism (Unio mancus Lamarck, 1819) to antifouling copper pyrithione |
| title_full | Oxidative stress response as biomarker of exposure of a freshwater invertebrate model organism (Unio mancus Lamarck, 1819) to antifouling copper pyrithione |
| title_fullStr | Oxidative stress response as biomarker of exposure of a freshwater invertebrate model organism (Unio mancus Lamarck, 1819) to antifouling copper pyrithione |
| title_full_unstemmed | Oxidative stress response as biomarker of exposure of a freshwater invertebrate model organism (Unio mancus Lamarck, 1819) to antifouling copper pyrithione |
| title_short | Oxidative stress response as biomarker of exposure of a freshwater invertebrate model organism (Unio mancus Lamarck, 1819) to antifouling copper pyrithione |
| title_sort | oxidative stress response as biomarker of exposure of a freshwater invertebrate model organism unio mancus lamarck 1819 to antifouling copper pyrithione |
| topic | biocides antifouling copper pyrithione biomarkers oxidative stress freshwater mussel |
| url | https://scindeks-clanci.ceon.rs/data/pdf/1820-3949/2022/1820-39492202063P.pdf |
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