Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases

Background and Aim: Procalcitonin is prohormone of calcitonin and is made 116 amino acids. The normal value of procalcitonin is less than 0.5 ng/ml, that if this amount exceeds, infection is indicated. This poly-peptide is a marker for the diagnosis of primary infection. Increased amounts of procalc...

Full description

Bibliographic Details
Main Authors: M Rahimkhani, N Einollani, R Sharifian
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2011-03-01
Series:پیاورد سلامت
Subjects:
Online Access:http://payavard.tums.ac.ir/article-1-95-en.html
_version_ 1819135293207347200
author M Rahimkhani
N Einollani
R Sharifian
author_facet M Rahimkhani
N Einollani
R Sharifian
author_sort M Rahimkhani
collection DOAJ
description Background and Aim: Procalcitonin is prohormone of calcitonin and is made 116 amino acids. The normal value of procalcitonin is less than 0.5 ng/ml, that if this amount exceeds, infection is indicated. This poly-peptide is a marker for the diagnosis of primary infection. Increased amounts of procalcitonin is associated with infection especially bacterial infections. Materials and Methods: 32 patients with liver cirrhosis and 16 healthy controls enrolled in this study were. Serum PCT levels in these subjects was measured. PCT level was measured by semi-quantitative method. Results: Patient group included 23 males and nine females with mean age of 45 years and SD= 17.44 years, the control group included 11 males and 5 females with mean age of 46 years and SD=15.5 years.The statistical analysis showed that there was significant difference between PCT levels in patients and controls (P<0.05).Furthermore PCT levels was significantly hgher in cirrhotic patients with hepatitisec background. Conclusion: Since these patients had no symptoms of infection and were hospitalized for endoscopy test and the PCT test was positive in 78.1% of cirrhotic patients ,whereas this ratio was 25% in the control group, the patients probably were infected and should be under proper treatment.
first_indexed 2024-12-22T10:16:47Z
format Article
id doaj.art-971a25810a494ea2a7e996605b461da3
institution Directory Open Access Journal
issn 1735-8132
2008-2665
language fas
last_indexed 2024-12-22T10:16:47Z
publishDate 2011-03-01
publisher Tehran University of Medical Sciences
record_format Article
series پیاورد سلامت
spelling doaj.art-971a25810a494ea2a7e996605b461da32022-12-21T18:29:43ZfasTehran University of Medical Sciencesپیاورد سلامت1735-81322008-26652011-03-01436066Survey Of Relationship Between Serum Procalcitonin And Infectious DiseasesM Rahimkhani0N Einollani1R Sharifian2 Background and Aim: Procalcitonin is prohormone of calcitonin and is made 116 amino acids. The normal value of procalcitonin is less than 0.5 ng/ml, that if this amount exceeds, infection is indicated. This poly-peptide is a marker for the diagnosis of primary infection. Increased amounts of procalcitonin is associated with infection especially bacterial infections. Materials and Methods: 32 patients with liver cirrhosis and 16 healthy controls enrolled in this study were. Serum PCT levels in these subjects was measured. PCT level was measured by semi-quantitative method. Results: Patient group included 23 males and nine females with mean age of 45 years and SD= 17.44 years, the control group included 11 males and 5 females with mean age of 46 years and SD=15.5 years.The statistical analysis showed that there was significant difference between PCT levels in patients and controls (P<0.05).Furthermore PCT levels was significantly hgher in cirrhotic patients with hepatitisec background. Conclusion: Since these patients had no symptoms of infection and were hospitalized for endoscopy test and the PCT test was positive in 78.1% of cirrhotic patients ,whereas this ratio was 25% in the control group, the patients probably were infected and should be under proper treatment.http://payavard.tums.ac.ir/article-1-95-en.htmlprocalcitonincirrhosisbacterial infection
spellingShingle M Rahimkhani
N Einollani
R Sharifian
Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases
پیاورد سلامت
procalcitonin
cirrhosis
bacterial infection
title Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases
title_full Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases
title_fullStr Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases
title_full_unstemmed Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases
title_short Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases
title_sort survey of relationship between serum procalcitonin and infectious diseases
topic procalcitonin
cirrhosis
bacterial infection
url http://payavard.tums.ac.ir/article-1-95-en.html
work_keys_str_mv AT mrahimkhani surveyofrelationshipbetweenserumprocalcitoninandinfectiousdiseases
AT neinollani surveyofrelationshipbetweenserumprocalcitoninandinfectiousdiseases
AT rsharifian surveyofrelationshipbetweenserumprocalcitoninandinfectiousdiseases