Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44.

Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44.

MASP-1 is the first protein in the activation of the lectin pathway and MASP-1 is, like its isoforms MASP-3 and MAp44, encoded by the MASP1 gene. Our aim was to explore associations between polymorphisms in MASP1 and corresponding concentrations of MASP-1, MASP-3, and MAp44 in plasma as well as the...

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Bibliographic Details
Main Authors: Christian Gytz Ammitzbøll, Rudi Steffensen, Hans Jørgen Nielsen, Steffen Thiel, Kristian Stengaard-Pedersen, Martin Bøgsted, Jens Christian Jensenius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3759447?pdf=render

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