Prion protein gene polymorphisms and accumulation of pathogenic prion protein (PrPSc) in a herd with previously confirmed scrapie cases

Prion protein gene polymorphisms and accumulation of pathogenic prion protein (PrPSc) in a herd with previously confirmed scrapie cases

Scrapie in sheep is associated with at least three polymorphisms in the prion protein gene (PRNP) on codons 136, 154, and 171. Countries where scrapie is endemic have been using breeding programs based on selection for the most resistant alleles. There are some PRNP genotyping data on sheep in Brazi...

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Bibliographic Details
Main Authors: Cristina Santos Sotomaior, David Driemeier, Juliano Leal, Rüdiger Daniel Ollhoff, Vanete Thomaz-Soccol
Format: Article
Language:English
Published: Universidade Federal de Uberlândia 2015-06-01
Series:Bioscience Journal
Subjects:
ovis aries
prpsc
prnp polymorphisms
genotyping
affected flock.
Online Access:http://www.seer.ufu.br/index.php/biosciencejournal/article/view/26231

Internet

http://www.seer.ufu.br/index.php/biosciencejournal/article/view/26231

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