Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic?
Objective: : This study aimed to describe the distribution of respiratory pathogens and the occurrence of co-pathogens during the first year of the COVID-19 pandemic. Methods: We used a multiplex polymerase chain reaction (PCR) panel targeting 23 microorganisms to analyze the oro-pharyngeal samples...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-03-01
|
| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971222000182 |
| _version_ | 1818987313069293568 |
|---|---|
| author | Or Kriger Shiraz Gefen-Halevi Eyal Leshem Gillian Smollan Natasha Belausov Aseel Egbarye Rawan Khashab Miran Odeh Adleen Saffia Yuval Barak Oswa Abu Hussein Rachel Hamias Yael Aharon Jacqueline Alfandari Ital Nemet Limor Kliker Hilda Sherbany Michal Mandelboim Sharon Amit |
| author_facet | Or Kriger Shiraz Gefen-Halevi Eyal Leshem Gillian Smollan Natasha Belausov Aseel Egbarye Rawan Khashab Miran Odeh Adleen Saffia Yuval Barak Oswa Abu Hussein Rachel Hamias Yael Aharon Jacqueline Alfandari Ital Nemet Limor Kliker Hilda Sherbany Michal Mandelboim Sharon Amit |
| author_sort | Or Kriger |
| collection | DOAJ |
| description | Objective: : This study aimed to describe the distribution of respiratory pathogens and the occurrence of co-pathogens during the first year of the COVID-19 pandemic. Methods: We used a multiplex polymerase chain reaction (PCR) panel targeting 23 microorganisms to analyze the oro-pharyngeal samples of patients admitted to our hospital with acute respiratory infection (ARI) between March 1, 2020, and February 28, 2021. We matched 40 to 50 patients who were SARS-CoV-2 positive and SARS-CoV-2 negative per month for age and sex. Results: A total of 939 patients with multiplex PCR test results were included in the study. Respiratory pathogens where detected in only 8/476 (1.6%) patients with COVID-19 versus 87/463 (18.7%) patients with non–COVID-19 ARI patients. Diversity and rates of pathogens vastly differed from previous years but showed seasonal variance. Conclusion: Patients with SARS-CoV-2 infection presenting with ARI during the first year of the COVID-19 pandemic demonstrated paucity of respiratory co-pathogens. |
| first_indexed | 2024-12-20T19:04:42Z |
| format | Article |
| id | doaj.art-9729391e901e4c4b85bbcbecb5ce2deb |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-20T19:04:42Z |
| publishDate | 2022-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-9729391e901e4c4b85bbcbecb5ce2deb2022-12-21T19:29:18ZengElsevierInternational Journal of Infectious Diseases1201-97122022-03-01116226229Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic?Or Kriger0Shiraz Gefen-Halevi1Eyal Leshem2Gillian Smollan3Natasha Belausov4Aseel Egbarye5Rawan Khashab6Miran Odeh7Adleen Saffia8Yuval Barak9Oswa Abu Hussein10Rachel Hamias11Yael Aharon12Jacqueline Alfandari13Ital Nemet14Limor Kliker15Hilda Sherbany16Michal Mandelboim17Sharon Amit18Sheba Medical Center, Ramat-Gan, Israel; Corresponding author: Clinical Microbiology, Sheba Medical Center, Ramat-Gan, Israel. Tel.: +972547860584. Telephone: +972547860584Sheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelSheba Medical Center, Ramat-Gan, IsraelCentral Virology Laboratory, Ministry of Health, Ramat-Gan, IsraelCentral Virology Laboratory, Ministry of Health, Ramat-Gan, IsraelCentral Virology Laboratory, Ministry of Health, Ramat-Gan, IsraelCentral Virology Laboratory, Ministry of Health, Ramat-Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelSheba Medical Center, Ramat-Gan, IsraelObjective: : This study aimed to describe the distribution of respiratory pathogens and the occurrence of co-pathogens during the first year of the COVID-19 pandemic. Methods: We used a multiplex polymerase chain reaction (PCR) panel targeting 23 microorganisms to analyze the oro-pharyngeal samples of patients admitted to our hospital with acute respiratory infection (ARI) between March 1, 2020, and February 28, 2021. We matched 40 to 50 patients who were SARS-CoV-2 positive and SARS-CoV-2 negative per month for age and sex. Results: A total of 939 patients with multiplex PCR test results were included in the study. Respiratory pathogens where detected in only 8/476 (1.6%) patients with COVID-19 versus 87/463 (18.7%) patients with non–COVID-19 ARI patients. Diversity and rates of pathogens vastly differed from previous years but showed seasonal variance. Conclusion: Patients with SARS-CoV-2 infection presenting with ARI during the first year of the COVID-19 pandemic demonstrated paucity of respiratory co-pathogens.http://www.sciencedirect.com/science/article/pii/S1201971222000182COVID-19SARS-CoV-2co-infections |
| spellingShingle | Or Kriger Shiraz Gefen-Halevi Eyal Leshem Gillian Smollan Natasha Belausov Aseel Egbarye Rawan Khashab Miran Odeh Adleen Saffia Yuval Barak Oswa Abu Hussein Rachel Hamias Yael Aharon Jacqueline Alfandari Ital Nemet Limor Kliker Hilda Sherbany Michal Mandelboim Sharon Amit Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic? International Journal of Infectious Diseases COVID-19 SARS-CoV-2 co-infections |
| title | Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic? |
| title_full | Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic? |
| title_fullStr | Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic? |
| title_full_unstemmed | Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic? |
| title_short | Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic? |
| title_sort | viral co pathogens in covid 19 acute respiratory syndrome what did we learn from the first year of pandemic |
| topic | COVID-19 SARS-CoV-2 co-infections |
| url | http://www.sciencedirect.com/science/article/pii/S1201971222000182 |
| work_keys_str_mv | AT orkriger viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT shirazgefenhalevi viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT eyalleshem viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT gilliansmollan viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT natashabelausov viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT aseelegbarye viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT rawankhashab viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT miranodeh viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT adleensaffia viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT yuvalbarak viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT oswaabuhussein viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT rachelhamias viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT yaelaharon viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT jacquelinealfandari viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT italnemet viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT limorkliker viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT hildasherbany viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT michalmandelboim viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic AT sharonamit viralcopathogensincovid19acuterespiratorysyndromewhatdidwelearnfromthefirstyearofpandemic |