MazF Endoribonucleolytic Toxin Conserved in <i>Nitrospira</i> Specifically Cleaves the AACU, AACG, and AAUU Motifs

MazF Endoribonucleolytic Toxin Conserved in <i>Nitrospira</i> Specifically Cleaves the AACU, AACG, and AAUU Motifs

MazF is an endoribonucleolytic toxin that cleaves intracellular RNAs in sequence-specific manners. It is liberated in bacterial cells in response to environmental changes and is suggested to contribute to bacterial survival by inducing translational regulation. Thus, determining the cleavage specifi...

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Bibliographic Details
Main Authors: Rie Aoi, Tatsuki Miyamoto, Akiko Yokota, Yuri Ota, Hirotsugu Fujitani, Satoshi Tsuneda, Naohiro Noda
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Toxins
Subjects:
<i>Nitrospira</i>
toxin-antitoxin systems
MazF
sequence-specificity
RNase
Online Access:https://www.mdpi.com/2072-6651/12/5/287

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