Co-transplantation of Epidermal Neural Crest Stem Cells and Olfactory Ensheathing Cells Repairs Sciatic Nerve Defects in Rats

Co-transplantation of Epidermal Neural Crest Stem Cells and Olfactory Ensheathing Cells Repairs Sciatic Nerve Defects in Rats

Cell-based therapy is an alternative strategy to improve outcomes of peripheral nerve injury (PNI). Epidermal neural crest stem cell (EPI-NCSC) is obtained from autologous tissue without immunological rejection, which could expand quickly in vitro and is suitable candidate for cell-based therapy. Ol...

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Bibliographic Details
Main Authors: Lu Zhang, Bingcang Li, Bin Liu, Zhifang Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
peripheral nerve injury
epidermal neural crest stem cell
olfactory ensheathing cell
co-transplantation
brain derived growth factor
nerve growth factor
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00253/full

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