Modification of porous polyethylene scaffolds for cell attachment and proliferation
Poulomi Sengupta, Sachin S Surwase, Bhagavatula LV Prasad Physical Chemistry Division, CSIR–National Chemical Laboratory, Pune, India Abstract: Synthetic polymers are widely researched for their use in tissue engineering. Control in size, surface area, pore size, and elasticity are the b...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2018-03-01
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| Series: | International Journal of Nanomedicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/modification-of-porous-polyethylene-scaffolds-for-cell-attachment-and--peer-reviewed-article-IJN |
| _version_ | 1818846140440772608 |
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| author | Sengupta P Surwase SS Prasad BLV |
| author_facet | Sengupta P Surwase SS Prasad BLV |
| author_sort | Sengupta P |
| collection | DOAJ |
| description | Poulomi Sengupta, Sachin S Surwase, Bhagavatula LV Prasad Physical Chemistry Division, CSIR–National Chemical Laboratory, Pune, India Abstract: Synthetic polymers are widely researched for their use in tissue engineering. Control in size, surface area, pore size, and elasticity are the biggest advantages of using a man-made polymer. However, often the polymers are hydrophobic (do not encourage cell attachment); hence, it is hugely challenging to integrate them with the normal tissues. Herein, we have tried to overcome this disadvantage of polymers by coating them with citrate-stabilized gold nanoparticles and arginine. High-density polyethylene, upon multiple treatments, shows low water contact angle, which encourages cell attachment and proliferation in comparison to the untreated polymers. Keywords: tissue engineering, gold nanoparticle, HDPE hydrophilicity |
| first_indexed | 2024-12-19T05:40:49Z |
| format | Article |
| id | doaj.art-972e07b86ac84dc8b3f21ef19ad63031 |
| institution | Directory Open Access Journal |
| issn | 1178-2013 |
| language | English |
| last_indexed | 2024-12-19T05:40:49Z |
| publishDate | 2018-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Nanomedicine |
| spelling | doaj.art-972e07b86ac84dc8b3f21ef19ad630312022-12-21T20:34:01ZengDove Medical PressInternational Journal of Nanomedicine1178-20132018-03-01Volume 13879037259Modification of porous polyethylene scaffolds for cell attachment and proliferationSengupta PSurwase SSPrasad BLVPoulomi Sengupta, Sachin S Surwase, Bhagavatula LV Prasad Physical Chemistry Division, CSIR–National Chemical Laboratory, Pune, India Abstract: Synthetic polymers are widely researched for their use in tissue engineering. Control in size, surface area, pore size, and elasticity are the biggest advantages of using a man-made polymer. However, often the polymers are hydrophobic (do not encourage cell attachment); hence, it is hugely challenging to integrate them with the normal tissues. Herein, we have tried to overcome this disadvantage of polymers by coating them with citrate-stabilized gold nanoparticles and arginine. High-density polyethylene, upon multiple treatments, shows low water contact angle, which encourages cell attachment and proliferation in comparison to the untreated polymers. Keywords: tissue engineering, gold nanoparticle, HDPE hydrophilicityhttps://www.dovepress.com/modification-of-porous-polyethylene-scaffolds-for-cell-attachment-and--peer-reviewed-article-IJNTissue engineeringGold nanoparticleHDPE Hydrophilicity |
| spellingShingle | Sengupta P Surwase SS Prasad BLV Modification of porous polyethylene scaffolds for cell attachment and proliferation International Journal of Nanomedicine Tissue engineering Gold nanoparticle HDPE Hydrophilicity |
| title | Modification of porous polyethylene scaffolds for cell attachment and proliferation |
| title_full | Modification of porous polyethylene scaffolds for cell attachment and proliferation |
| title_fullStr | Modification of porous polyethylene scaffolds for cell attachment and proliferation |
| title_full_unstemmed | Modification of porous polyethylene scaffolds for cell attachment and proliferation |
| title_short | Modification of porous polyethylene scaffolds for cell attachment and proliferation |
| title_sort | modification of porous polyethylene scaffolds for cell attachment and proliferation |
| topic | Tissue engineering Gold nanoparticle HDPE Hydrophilicity |
| url | https://www.dovepress.com/modification-of-porous-polyethylene-scaffolds-for-cell-attachment-and--peer-reviewed-article-IJN |
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