Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome
The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is an uncommon cause of cardiac hypertrophy, fibrosis, and dysfunction. It shares similar features to numerous other causes of left ventricular hypertrophy, and therefore, because of its rarity, ma...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-02-01
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| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/11/2/295 |
| _version_ | 1797396757031682048 |
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| author | Anna B. Reid Luigi Venetucci Matthias Schmitt Gaetano Nucifora |
| author_facet | Anna B. Reid Luigi Venetucci Matthias Schmitt Gaetano Nucifora |
| author_sort | Anna B. Reid |
| collection | DOAJ |
| description | The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is an uncommon cause of cardiac hypertrophy, fibrosis, and dysfunction. It shares similar features to numerous other causes of left ventricular hypertrophy, and therefore, because of its rarity, may not be immediately considered as a diagnosis. Prompt recognition of clinical and cardiac imaging features may expedite diagnosis and management. We report the case of a 38-year-old man admitted with neurological symptoms and in whom the diagnostic workup led to the diagnosis of MELAS syndrome with cardiac involvement. |
| first_indexed | 2024-03-09T00:55:45Z |
| format | Article |
| id | doaj.art-972ea89056344ecdb99192f7c1586006 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T00:55:45Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-972ea89056344ecdb99192f7c15860062023-12-11T16:53:57ZengMDPI AGDiagnostics2075-44182021-02-0111229510.3390/diagnostics11020295Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS SyndromeAnna B. Reid0Luigi Venetucci1Matthias Schmitt2Gaetano Nucifora3Cardiac Imaging Unit, North West Heart Centre, Manchester University NHS Foundation Trust, Manchester M23 9LT, UKManchester Heart Centre, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester M13 9WL, UKCardiac Imaging Unit, North West Heart Centre, Manchester University NHS Foundation Trust, Manchester M23 9LT, UKCardiac Imaging Unit, North West Heart Centre, Manchester University NHS Foundation Trust, Manchester M23 9LT, UKThe mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is an uncommon cause of cardiac hypertrophy, fibrosis, and dysfunction. It shares similar features to numerous other causes of left ventricular hypertrophy, and therefore, because of its rarity, may not be immediately considered as a diagnosis. Prompt recognition of clinical and cardiac imaging features may expedite diagnosis and management. We report the case of a 38-year-old man admitted with neurological symptoms and in whom the diagnostic workup led to the diagnosis of MELAS syndrome with cardiac involvement.https://www.mdpi.com/2075-4418/11/2/295cardiac magnetic resonancehypertrophic cardiomyopathyleft ventricular hypertrophyMELAS syndrome |
| spellingShingle | Anna B. Reid Luigi Venetucci Matthias Schmitt Gaetano Nucifora Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome Diagnostics cardiac magnetic resonance hypertrophic cardiomyopathy left ventricular hypertrophy MELAS syndrome |
| title | Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome |
| title_full | Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome |
| title_fullStr | Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome |
| title_full_unstemmed | Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome |
| title_short | Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome |
| title_sort | unraveling an unusual phenocopy of hypertrophic cardiomyopathy melas syndrome |
| topic | cardiac magnetic resonance hypertrophic cardiomyopathy left ventricular hypertrophy MELAS syndrome |
| url | https://www.mdpi.com/2075-4418/11/2/295 |
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