Inhibitory Effect of Triterpenoids from Dillenia serrata (Dilleniaceae) on Prostaglandin E2 Production and Quantitative HPLC Analysis of Its Koetjapic Acid and Betulinic Acid Contents

Inhibitory Effect of Triterpenoids from Dillenia serrata (Dilleniaceae) on Prostaglandin E2 Production and Quantitative HPLC Analysis of Its Koetjapic Acid and Betulinic Acid Contents

The crude methanol extracts and fractions of the root and stem barks of Dillenia serrata Thunb. showed 64% to 73% inhibition on the production of prostaglandin E2 (PGE2) in lipopolysaccharide-induced human whole blood using a radioimmunoassay technique. Three triterpenoids isolated from the root ba...

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Bibliographic Details
Main Authors: Juriyati Jalil, Carla W. Sabandar, Norizan Ahmat, Jamia A. Jamal, Ibrahim Jantan, Nor-Ashila Aladdin, Kartiniwati Muhammad, Fhataheya Buang, Hazni Falina Mohamad, Idin Sahidin
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Molecules
Subjects:
Dilleniaceae
Dillenia serrata
triterpenoids
prostaglandin E2
HPLC
Online Access:http://www.mdpi.com/1420-3049/20/2/3206

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