Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination

Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination

Summary: Remyelination requires the generation of new oligodendrocytes (OLs), which are derived from oligodendrocyte progenitor cells (OPCs). Maturation of OPCs into OLs is a multi-step process. Here, we describe a microRNA expressed by OLs, miR-27a, as a regulator of OL development and survival. In...

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Bibliographic Details
Main Authors: Ajai Tripathi, Christina Volsko, Jessie P. Garcia, Eneritz Agirre, Kevin C. Allan, Paul J. Tesar, Bruce D. Trapp, Goncalo Castelo-Branco, Fraser J. Sim, Ranjan Dutta
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719311970

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