Retro-Mode in NIDEK Mirante: A Comparative Analysis with Other Imaging Modalities for AMD and CSR

Background: Retro-mode is a novel technique capable of creating pseudo-3D images of the retina. However, its clinical utility remains unknown. This study aimed to evaluate the Nidek Mirante multimodal imaging platform for ocular assessment in patients with various retinal conditions. Methods: A tota...

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Main Authors: Adam Wylęgała, Przemysław Wozniak, Bogumiła Sędziak-Marcinek, Bartłomiej Bolek, Dominika Szkodny, Edward Wylęgała
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/17/2846
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author Adam Wylęgała
Przemysław Wozniak
Bogumiła Sędziak-Marcinek
Bartłomiej Bolek
Dominika Szkodny
Edward Wylęgała
author_facet Adam Wylęgała
Przemysław Wozniak
Bogumiła Sędziak-Marcinek
Bartłomiej Bolek
Dominika Szkodny
Edward Wylęgała
author_sort Adam Wylęgała
collection DOAJ
description Background: Retro-mode is a novel technique capable of creating pseudo-3D images of the retina. However, its clinical utility remains unknown. This study aimed to evaluate the Nidek Mirante multimodal imaging platform for ocular assessment in patients with various retinal conditions. Methods: A total of 115 participants with central serous chorioretinopathy (CSR) and age-related macular degeneration (AMD) were included. Two experienced graders independently evaluated the images, and statistical analysis was performed to assess interclass correlation coefficients (ICC) between graders and modalities; Results: For CSR detection, retro-mode demonstrated exceptionally high ICC rates (ICC = 1; 100%), while color and autofluorescence (FAF) showed moderate coefficients (0.69 and 0.78, respectively). The detection of pigment epithelial detachment was high across all methods, with only retro-mode deviated right (DR) allowing detection in 69% of cases, while retro-mode DR and deviated left (DL) achieved 100% detection. FAF-green achieved a 95% detection rate. In detecting retinal atrophy, most modalities demonstrated high detection rates, with the lowest detection rates offered by retro-mode DL (ICC = 0.85) and DR (ICC = 0.89), while retro-mode ring aperture offered 0.97. Infra-red and fluorescein angiography imaging offered the highest detection rates among the tested modalities, with 97% and 100%, respectively. Conclusion: Retro-mode showed promise for comprehensive ocular evaluation and diagnosis, with certain imaging modalities demonstrating higher accuracy in detecting specific retinal features.
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spelling doaj.art-973834679a8e4818a3fe44488d73e2982023-11-19T08:00:22ZengMDPI AGDiagnostics2075-44182023-09-011317284610.3390/diagnostics13172846Retro-Mode in NIDEK Mirante: A Comparative Analysis with Other Imaging Modalities for AMD and CSRAdam Wylęgała0Przemysław Wozniak1Bogumiła Sędziak-Marcinek2Bartłomiej Bolek3Dominika Szkodny4Edward Wylęgała5Health Promotion and Obesity Management, Pathophysiology Department, Medical University of Silesia in Katowice, 40-752 Katowice, PolandChair and Clinical Department of Ophthalmology, School of Medicine in Zabrze, Medical University of Silesia in Katowice, District Railway Hospital, 40-760 Katowice, PolandChair and Clinical Department of Ophthalmology, School of Medicine in Zabrze, Medical University of Silesia in Katowice, District Railway Hospital, 40-760 Katowice, PolandChair and Clinical Department of Ophthalmology, School of Medicine in Zabrze, Medical University of Silesia in Katowice, District Railway Hospital, 40-760 Katowice, PolandChair and Clinical Department of Ophthalmology, School of Medicine in Zabrze, Medical University of Silesia in Katowice, District Railway Hospital, 40-760 Katowice, PolandChair and Clinical Department of Ophthalmology, School of Medicine in Zabrze, Medical University of Silesia in Katowice, District Railway Hospital, 40-760 Katowice, PolandBackground: Retro-mode is a novel technique capable of creating pseudo-3D images of the retina. However, its clinical utility remains unknown. This study aimed to evaluate the Nidek Mirante multimodal imaging platform for ocular assessment in patients with various retinal conditions. Methods: A total of 115 participants with central serous chorioretinopathy (CSR) and age-related macular degeneration (AMD) were included. Two experienced graders independently evaluated the images, and statistical analysis was performed to assess interclass correlation coefficients (ICC) between graders and modalities; Results: For CSR detection, retro-mode demonstrated exceptionally high ICC rates (ICC = 1; 100%), while color and autofluorescence (FAF) showed moderate coefficients (0.69 and 0.78, respectively). The detection of pigment epithelial detachment was high across all methods, with only retro-mode deviated right (DR) allowing detection in 69% of cases, while retro-mode DR and deviated left (DL) achieved 100% detection. FAF-green achieved a 95% detection rate. In detecting retinal atrophy, most modalities demonstrated high detection rates, with the lowest detection rates offered by retro-mode DL (ICC = 0.85) and DR (ICC = 0.89), while retro-mode ring aperture offered 0.97. Infra-red and fluorescein angiography imaging offered the highest detection rates among the tested modalities, with 97% and 100%, respectively. Conclusion: Retro-mode showed promise for comprehensive ocular evaluation and diagnosis, with certain imaging modalities demonstrating higher accuracy in detecting specific retinal features.https://www.mdpi.com/2075-4418/13/17/2846retro-modeNidekFAFmultimodal imagingMirante
spellingShingle Adam Wylęgała
Przemysław Wozniak
Bogumiła Sędziak-Marcinek
Bartłomiej Bolek
Dominika Szkodny
Edward Wylęgała
Retro-Mode in NIDEK Mirante: A Comparative Analysis with Other Imaging Modalities for AMD and CSR
Diagnostics
retro-mode
Nidek
FAF
multimodal imaging
Mirante
title Retro-Mode in NIDEK Mirante: A Comparative Analysis with Other Imaging Modalities for AMD and CSR
title_full Retro-Mode in NIDEK Mirante: A Comparative Analysis with Other Imaging Modalities for AMD and CSR
title_fullStr Retro-Mode in NIDEK Mirante: A Comparative Analysis with Other Imaging Modalities for AMD and CSR
title_full_unstemmed Retro-Mode in NIDEK Mirante: A Comparative Analysis with Other Imaging Modalities for AMD and CSR
title_short Retro-Mode in NIDEK Mirante: A Comparative Analysis with Other Imaging Modalities for AMD and CSR
title_sort retro mode in nidek mirante a comparative analysis with other imaging modalities for amd and csr
topic retro-mode
Nidek
FAF
multimodal imaging
Mirante
url https://www.mdpi.com/2075-4418/13/17/2846
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AT bogumiłasedziakmarcinek retromodeinnidekmiranteacomparativeanalysiswithotherimagingmodalitiesforamdandcsr
AT bartłomiejbolek retromodeinnidekmiranteacomparativeanalysiswithotherimagingmodalitiesforamdandcsr
AT dominikaszkodny retromodeinnidekmiranteacomparativeanalysiswithotherimagingmodalitiesforamdandcsr
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