Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode.
<h4>Purpose</h4>This study aimed to examine the validity, reliability and minimum detectable change (MDC) of the Cosmed K5 in breath by breath (BxB) mode, against VacuMed metabolic simulator. Intra and inter-units reliability was also assessed.<h4>Methods</h4>Fourteen metabol...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0209925 |
| _version_ | 1819112695534714880 |
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| author | Laura Guidetti Marco Meucci Francesco Bolletta Gian Pietro Emerenziani Maria Chiara Gallotta Carlo Baldari |
| author_facet | Laura Guidetti Marco Meucci Francesco Bolletta Gian Pietro Emerenziani Maria Chiara Gallotta Carlo Baldari |
| author_sort | Laura Guidetti |
| collection | DOAJ |
| description | <h4>Purpose</h4>This study aimed to examine the validity, reliability and minimum detectable change (MDC) of the Cosmed K5 in breath by breath (BxB) mode, against VacuMed metabolic simulator. Intra and inter-units reliability was also assessed.<h4>Methods</h4>Fourteen metabolic rates (from 0.9 to 4 L.min-1) were reproduced by a VacuMed system and pulmonary ventilation (VE), oxygen consumption (VO2) and carbon dioxide production (VCO2) were measured by two different K5 units. Validity was assessed by ordinary least products (OLP) regression analysis, Bland-Altman plots, intraclass correlation coefficients (ICC), mean percentage differences, technical errors (TE) and MDC for VE, VO2, and VCO2. Intra- and inter-K5 reliability was evaluated by absolute percentage differences between measurements (MAPE), ICCs, TE, and MDC.<h4>Results</h4>Validity analysis from OLP regression data and Bland- Altman plots indicated high agreement between K5 and simulator. ICC values were excellent for all variables (>0.99). Mean percentage differences in VE (-0.50%, p = 0.11), VO2 (-0.04%, p = 0.80), and VCO2 (-1.03%, p = 0.09) showed no significant bias. The technical error (TE) ranged from 0.73% to 1.34% (VE and VCO2 respectively). MDC were lower than 4% (VE = 2.0%, VO2 = 3.8%, VCO2 = 3.7%). The intra and inter K5 reliability assessment reveled excellent ICCs (>0.99), MAPE <2% (no significant differences between trials), TE < or around 1%, MDC <or around 3%.<h4>Conclusions</h4>K5 in BxB mode is a valid and reliable system for metabolic measurements. This is the first study assessing the MDC accounting only for technical variability reporting intra- and inter-units MDCs <3.3%. |
| first_indexed | 2024-12-22T04:17:36Z |
| format | Article |
| id | doaj.art-973c1729d98b4c3d8c8eff26b8e40780 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T04:17:36Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-973c1729d98b4c3d8c8eff26b8e407802022-12-21T18:39:22ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-011312e020992510.1371/journal.pone.0209925Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode.Laura GuidettiMarco MeucciFrancesco BollettaGian Pietro EmerenzianiMaria Chiara GallottaCarlo Baldari<h4>Purpose</h4>This study aimed to examine the validity, reliability and minimum detectable change (MDC) of the Cosmed K5 in breath by breath (BxB) mode, against VacuMed metabolic simulator. Intra and inter-units reliability was also assessed.<h4>Methods</h4>Fourteen metabolic rates (from 0.9 to 4 L.min-1) were reproduced by a VacuMed system and pulmonary ventilation (VE), oxygen consumption (VO2) and carbon dioxide production (VCO2) were measured by two different K5 units. Validity was assessed by ordinary least products (OLP) regression analysis, Bland-Altman plots, intraclass correlation coefficients (ICC), mean percentage differences, technical errors (TE) and MDC for VE, VO2, and VCO2. Intra- and inter-K5 reliability was evaluated by absolute percentage differences between measurements (MAPE), ICCs, TE, and MDC.<h4>Results</h4>Validity analysis from OLP regression data and Bland- Altman plots indicated high agreement between K5 and simulator. ICC values were excellent for all variables (>0.99). Mean percentage differences in VE (-0.50%, p = 0.11), VO2 (-0.04%, p = 0.80), and VCO2 (-1.03%, p = 0.09) showed no significant bias. The technical error (TE) ranged from 0.73% to 1.34% (VE and VCO2 respectively). MDC were lower than 4% (VE = 2.0%, VO2 = 3.8%, VCO2 = 3.7%). The intra and inter K5 reliability assessment reveled excellent ICCs (>0.99), MAPE <2% (no significant differences between trials), TE < or around 1%, MDC <or around 3%.<h4>Conclusions</h4>K5 in BxB mode is a valid and reliable system for metabolic measurements. This is the first study assessing the MDC accounting only for technical variability reporting intra- and inter-units MDCs <3.3%.https://doi.org/10.1371/journal.pone.0209925 |
| spellingShingle | Laura Guidetti Marco Meucci Francesco Bolletta Gian Pietro Emerenziani Maria Chiara Gallotta Carlo Baldari Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode. PLoS ONE |
| title | Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode. |
| title_full | Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode. |
| title_fullStr | Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode. |
| title_full_unstemmed | Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode. |
| title_short | Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode. |
| title_sort | validity reliability and minimum detectable change of cosmed k5 portable gas exchange system in breath by breath mode |
| url | https://doi.org/10.1371/journal.pone.0209925 |
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