Comparison of the ATB® Fungus 2 with the AFST-EUCAST for in vitro susceptibility testing of Candida spp

The increase of diseases caused by Candida spp., and the treatment failures, has underscored the need for testing the susceptibilities to antifungal agents. The commercial panel ATB® Fungus 2 was compared with the reference testing method of the European Subcommittee on Antifungal Susceptibility Tes...

Full description

Bibliographic Details
Main Authors: Jehidys Estella Montiel Ramos, Andrea Corrales Bernal, María Paulina Vélez Bravo, Armando Baena Zapata, Ana Cecilia Mesa Arango
Format: Article
Language:English
Published: Publicaciones UIS 2014-04-01
Series:Salud UIS
Subjects:
Online Access:http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-08072014000100002&lng=en&tlng=en
_version_ 1797719167485345792
author Jehidys Estella Montiel Ramos
Andrea Corrales Bernal
María Paulina Vélez Bravo
Armando Baena Zapata
Ana Cecilia Mesa Arango
author_facet Jehidys Estella Montiel Ramos
Andrea Corrales Bernal
María Paulina Vélez Bravo
Armando Baena Zapata
Ana Cecilia Mesa Arango
author_sort Jehidys Estella Montiel Ramos
collection DOAJ
description The increase of diseases caused by Candida spp., and the treatment failures, has underscored the need for testing the susceptibilities to antifungal agents. The commercial panel ATB® Fungus 2 was compared with the reference testing method of the European Subcommittee on Antifungal Susceptibility Testing of the Committee on Antimicrobial Susceptibility Testing (AFST-EUCAST) for the evaluation of the susceptibility of isolates of Candida spp. to three agents. The percentage of agreement was calculated based on the minimum inhibitory concentrations. There was a high correlation for AMB (100% қ = 1.0 Bhapkar coefficient p = 1.0); while it was lower with azoles (85%, қ = 0.41, p = Bhapkar coefficient 0.02 and 83.0%, қ = 0.15, Bhapkar coefficient p = 0.0006, respectively). The ATB® Fungus 2 and AFST-EUCAST are fully comparable methods for testing the susceptibility to AMB and to lesser extend comparable for ITR and FCA
first_indexed 2024-03-12T09:01:07Z
format Article
id doaj.art-973f3b50d40e4a2591fbbbfcf6bff760
institution Directory Open Access Journal
issn 0121-0807
language English
last_indexed 2024-03-12T09:01:07Z
publishDate 2014-04-01
publisher Publicaciones UIS
record_format Article
series Salud UIS
spelling doaj.art-973f3b50d40e4a2591fbbbfcf6bff7602023-09-02T15:40:54ZengPublicaciones UISSalud UIS0121-08072014-04-01461714S0121-08072014000100002Comparison of the ATB® Fungus 2 with the AFST-EUCAST for in vitro susceptibility testing of Candida sppJehidys Estella Montiel Ramos0Andrea Corrales Bernal1María Paulina Vélez Bravo2Armando Baena Zapata3Ana Cecilia Mesa Arango4Universidad de AntioquiaUniversidad de AntioquiaUniversidad de AntioquiaUniversidad de AntioquiaUniversidad de AntioquiaThe increase of diseases caused by Candida spp., and the treatment failures, has underscored the need for testing the susceptibilities to antifungal agents. The commercial panel ATB® Fungus 2 was compared with the reference testing method of the European Subcommittee on Antifungal Susceptibility Testing of the Committee on Antimicrobial Susceptibility Testing (AFST-EUCAST) for the evaluation of the susceptibility of isolates of Candida spp. to three agents. The percentage of agreement was calculated based on the minimum inhibitory concentrations. There was a high correlation for AMB (100% қ = 1.0 Bhapkar coefficient p = 1.0); while it was lower with azoles (85%, қ = 0.41, p = Bhapkar coefficient 0.02 and 83.0%, қ = 0.15, Bhapkar coefficient p = 0.0006, respectively). The ATB® Fungus 2 and AFST-EUCAST are fully comparable methods for testing the susceptibility to AMB and to lesser extend comparable for ITR and FCAhttp://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-08072014000100002&lng=en&tlng=enantifungal susceptibilityCandida sppATB® Fungus 2AFST-EUCASTsusceptibilidad antifúngicaCandida sppATB® Fungus 2AFST-EUCAST
spellingShingle Jehidys Estella Montiel Ramos
Andrea Corrales Bernal
María Paulina Vélez Bravo
Armando Baena Zapata
Ana Cecilia Mesa Arango
Comparison of the ATB® Fungus 2 with the AFST-EUCAST for in vitro susceptibility testing of Candida spp
Salud UIS
antifungal susceptibility
Candida spp
ATB® Fungus 2
AFST-EUCAST
susceptibilidad antifúngica
Candida spp
ATB® Fungus 2
AFST-EUCAST
title Comparison of the ATB® Fungus 2 with the AFST-EUCAST for in vitro susceptibility testing of Candida spp
title_full Comparison of the ATB® Fungus 2 with the AFST-EUCAST for in vitro susceptibility testing of Candida spp
title_fullStr Comparison of the ATB® Fungus 2 with the AFST-EUCAST for in vitro susceptibility testing of Candida spp
title_full_unstemmed Comparison of the ATB® Fungus 2 with the AFST-EUCAST for in vitro susceptibility testing of Candida spp
title_short Comparison of the ATB® Fungus 2 with the AFST-EUCAST for in vitro susceptibility testing of Candida spp
title_sort comparison of the atb r fungus 2 with the afst eucast for in vitro susceptibility testing of candida spp
topic antifungal susceptibility
Candida spp
ATB® Fungus 2
AFST-EUCAST
susceptibilidad antifúngica
Candida spp
ATB® Fungus 2
AFST-EUCAST
url http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-08072014000100002&lng=en&tlng=en
work_keys_str_mv AT jehidysestellamontielramos comparisonoftheatbfungus2withtheafsteucastforinvitrosusceptibilitytestingofcandidaspp
AT andreacorralesbernal comparisonoftheatbfungus2withtheafsteucastforinvitrosusceptibilitytestingofcandidaspp
AT mariapaulinavelezbravo comparisonoftheatbfungus2withtheafsteucastforinvitrosusceptibilitytestingofcandidaspp
AT armandobaenazapata comparisonoftheatbfungus2withtheafsteucastforinvitrosusceptibilitytestingofcandidaspp
AT anaceciliamesaarango comparisonoftheatbfungus2withtheafsteucastforinvitrosusceptibilitytestingofcandidaspp