Practical Approaches for Knock-Out Gene Editing in Pigs

Practical Approaches for Knock-Out Gene Editing in Pigs

Pigs are an important resource for meat production and serve as a model for human diseases. Due to their physiological and anatomical similarities to humans, these animals can recapitulate symptoms of human diseases, becoming an effective model for biomedical research. Although, in the past pig have...

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Bibliographic Details
Main Authors: Laura Daniela Ratner, Gaston Emilio La Motta, Olinda Briski, Daniel Felipe Salamone, Rafael Fernandez-Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
CRISPR-Cas9
knock-out
electroporation
microinjection
porcine zygotes
SCNT
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.617850/full

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