Screening for diminished ovarian reserve in Portugal: a cost-saving answer to shorten the fertility journey
Aim: Assess the budget impact of nationwide screening for diminished ovarian reserve (OR), via anti-Mu¨ llerian hormone (AMH) levels, to the Portugal National Health System (NHS). Patients & methods: The clinical journey was determined using literature and the family planning decision-making...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Becaris Publishing Limited
2023-06-01
|
| Series: | Journal of Comparative Effectiveness Research |
| Subjects: |
| _version_ | 1797688117602287616 |
|---|---|
| author | Pedro Xavier Sofia Dantas Teresa Almeida-Santos Sergio Reis Soares Ryan J Imhoff Victoria Genovez Catia Modesto Helena Gens Ines Correia Carlos Catalao |
| author_facet | Pedro Xavier Sofia Dantas Teresa Almeida-Santos Sergio Reis Soares Ryan J Imhoff Victoria Genovez Catia Modesto Helena Gens Ines Correia Carlos Catalao |
| author_sort | Pedro Xavier |
| collection | DOAJ |
| description | Aim: Assess the budget impact of nationwide screening for diminished ovarian reserve (OR), via
anti-Mu¨ llerian hormone (AMH) levels, to the Portugal National Health System (NHS). Patients &
methods: The clinical journey was determined using literature and the family planning decision-making
process/response using survey results. A panel of four local clinicians validated all assumptions/inputs.
Results: Screening for OR led to an expected savings of € 9.4 million for the NHS, driven by a 24%
reduction in medically assisted reproduction (MAR) use. When needed, referral for MAR was earlier and
more women used first-line versus second-line techniques. The model estimated a 12% decrease in failure.
Conclusion: This model shows AMH screening may allow more informed decisions, leading to a shorter
fertility journey, more efficient use of treatments, and substantial cost-savings for the NHS. |
| first_indexed | 2024-03-12T01:27:25Z |
| format | Article |
| id | doaj.art-9740e823e0bd499e8daba1ae6017392b |
| institution | Directory Open Access Journal |
| issn | 2042-6313 |
| language | English |
| last_indexed | 2024-03-12T01:27:25Z |
| publishDate | 2023-06-01 |
| publisher | Becaris Publishing Limited |
| record_format | Article |
| series | Journal of Comparative Effectiveness Research |
| spelling | doaj.art-9740e823e0bd499e8daba1ae6017392b2023-09-12T14:45:01ZengBecaris Publishing LimitedJournal of Comparative Effectiveness Research2042-63132023-06-0112710.57264/cer-2023-0003Screening for diminished ovarian reserve in Portugal: a cost-saving answer to shorten the fertility journeyPedro Xavier0Sofia Dantas1Teresa Almeida-Santos2Sergio Reis Soares3Ryan J Imhoff4https://orcid.org/0000-0002-4786-1401Victoria Genovez5Catia Modesto6Helena Gens7Ines Correia8Carlos Catalao9President of the Portuguese Society of Reproductive Medicine (SPMR); Gynaecology-Obstetrics specialist, sub-speciality in Reproductive Medicine, Centre for Reproduction Genetics Prof. Alberto Barros, 4100-021, PortugalGynaecology-Obstetrics specialist, sub-speciality in Reproductive Medicine, Hospital Senhora da Oliveira, Guimaraes, 4835-044, PortugalGynaecology-Obstetrics specialist, sub-speciality in Reproductive Medicine, Centro Hospitalar Universitario de Coimbra (CHUC), Coimbra, 3004-561, PortugalGynaecology-Obstetrics specialist, sub-speciality in Reproductive Medicine, IVI (Instituto Valenciano de Infertilidade), Lisbon, 1800-282, PortugalResearch Scientist II, CTI Clinical Trial & Consulting Services, Covington, KY 41011, USAMarket Access Associate II, CTI Clinical Trial & Consulting Services Portugal, Lisbon, 1072-274, PortugalHTA & Market Access Associate II, CTI Clinical Trial & Consulting Services Portugal, Lisbon, 1070-274, PortugalMedical Affairs Lead, Roche Sistemas de Diagnosticos, Amadora, 2720-413, PortugalMedical Science Liaison, Roche Sistemas de Diagnosticos, Amadora, 2720-413, PortugalAccess & Innovation Director, Roche Sistemas de Diagnosticos, Amadora, 2720-413, PortugalAim: Assess the budget impact of nationwide screening for diminished ovarian reserve (OR), via anti-Mu¨ llerian hormone (AMH) levels, to the Portugal National Health System (NHS). Patients & methods: The clinical journey was determined using literature and the family planning decision-making process/response using survey results. A panel of four local clinicians validated all assumptions/inputs. Results: Screening for OR led to an expected savings of € 9.4 million for the NHS, driven by a 24% reduction in medically assisted reproduction (MAR) use. When needed, referral for MAR was earlier and more women used first-line versus second-line techniques. The model estimated a 12% decrease in failure. Conclusion: This model shows AMH screening may allow more informed decisions, leading to a shorter fertility journey, more efficient use of treatments, and substantial cost-savings for the NHS.anti-mullerian hormoneassisted reproductive technologybirth ratecost analysiseconomic evaluationfamily planningfertilityovarian reservescreening |
| spellingShingle | Pedro Xavier Sofia Dantas Teresa Almeida-Santos Sergio Reis Soares Ryan J Imhoff Victoria Genovez Catia Modesto Helena Gens Ines Correia Carlos Catalao Screening for diminished ovarian reserve in Portugal: a cost-saving answer to shorten the fertility journey Journal of Comparative Effectiveness Research anti-mullerian hormone assisted reproductive technology birth rate cost analysis economic evaluation family planning fertility ovarian reserve screening |
| title | Screening for diminished ovarian reserve in Portugal: a cost-saving answer to shorten the fertility journey |
| title_full | Screening for diminished ovarian reserve in Portugal: a cost-saving answer to shorten the fertility journey |
| title_fullStr | Screening for diminished ovarian reserve in Portugal: a cost-saving answer to shorten the fertility journey |
| title_full_unstemmed | Screening for diminished ovarian reserve in Portugal: a cost-saving answer to shorten the fertility journey |
| title_short | Screening for diminished ovarian reserve in Portugal: a cost-saving answer to shorten the fertility journey |
| title_sort | screening for diminished ovarian reserve in portugal a cost saving answer to shorten the fertility journey |
| topic | anti-mullerian hormone assisted reproductive technology birth rate cost analysis economic evaluation family planning fertility ovarian reserve screening |
| work_keys_str_mv | AT pedroxavier screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT sofiadantas screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT teresaalmeidasantos screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT sergioreissoares screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT ryanjimhoff screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT victoriagenovez screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT catiamodesto screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT helenagens screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT inescorreia screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney AT carloscatalao screeningfordiminishedovarianreserveinportugalacostsavinganswertoshortenthefertilityjourney |