Optimal treatment for post-MI heart failure in rats: dapagliflozin first, adding sacubitril-valsartan 2 weeks later

Optimal treatment for post-MI heart failure in rats: dapagliflozin first, adding sacubitril-valsartan 2 weeks later

BackgroundBased on previous research, both dapagliflozin (DAPA) and sacubitril-valsartan (S/V) improve the prognosis of patients with heart failure (HF). Our study aims to investigate whether the early initiation of DAPA or the combination of DAPA with S/V in different orders would exert a greater p...

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Bibliographic Details
Main Authors: Wenqi Tao, Xiaoyu Yang, Qing Zhang, Shuli Bi, Zhuhua Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
myocardial Infarction
heart failure
dapagliflozin
sacubitril-valsartan
sequential administration
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1181473/full

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